马尔尼菲青霉的限制性内切酶分析。
Restriction endonuclease analysis of Penicillium marneffei.
作者信息
Vanittanakom N, Cooper C R, Chariyalertsak S, Youngchim S, Nelson K E, Sirisanthana T
机构信息
Department of Microbiology, Faculty of Medicine, Chiang Mai University, Thailand.
出版信息
J Clin Microbiol. 1996 Jul;34(7):1834-6. doi: 10.1128/JCM.34.7.1834-1836.1996.
Abstract
Forty-six isolates of Penicillium marneffei were differentiated into two DNA types on the basis of their restriction fragment length polymorphisms. Of the 22 human isolates of P. marneffei, 16 (72.7%) were type I and 6 (27.3%) were type II. Of the 23 bamboo rat isolates, 20 from Rhizomys sumatrensis were type I and 3 from Cannomys badius were type II. The soil isolate was type II. These data represent the first molecular epidemiological study of this important emerging fungal pathogen.
摘要
根据限制性片段长度多态性，46株马尔尼菲青霉菌株被分为两种DNA类型。在22株人类分离的马尔尼菲青霉菌株中，16株（72.7%）为I型，6株（27.3%）为II型。在23株竹鼠分离株中，20株来自苏门答腊竹鼠的为I型，3株来自大竹鼠的为II型。土壤分离株为II型。这些数据代表了对这种重要的新出现真菌病原体的首次分子流行病学研究。
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