Caldwell C J, Barrett W Y, Breuer J, Farmer S F, Swash M
Department of Morbid Anatomy, London Hospital Medical College, U.K.
Neuromuscul Disord. 1996 May;6(3):151-4. doi: 10.1016/0960-8966(96)00008-9.
The case is described of an HTLV-1 seropositive Jamaican woman who presented with signs and symptoms of polymyositis and myelopathy. A muscle biopsy showed features of myositis with a mononuclear inflammatory infiltrate, variation in fibre size and evidence of regeneration. Immunocytochemistry showed the mononuclear cells were composed of macrophages and T-lymphocytes suggesting a cell-mediated response. Multiplex PCR demonstrated the presence of the HTLV-1 tax gene within the muscle.
本文描述了一名HTLV-1血清阳性的牙买加女性病例，该患者出现了多发性肌炎和脊髓病的体征和症状。肌肉活检显示有肌炎特征，伴有单核细胞炎性浸润、纤维大小变异和再生证据。免疫细胞化学显示单核细胞由巨噬细胞和T淋巴细胞组成，提示细胞介导的反应。多重PCR证明肌肉内存在HTLV-1 tax基因。
