Kragballe K
Department of Dermatology, Marselisborg Hospital, University of Aarhus, Denmark.
Dermatol Clin. 1995 Oct;13(4):835-9.
The natural form of vitamin D3, 1,25-dihydroxyvitamin D3, modulates epidermal proliferation and differentiation and inhibits immune induction. Calcipotriol (calcipotriene) is a synthetic vitamin D analogue that partially separates the newly identified effects from the classic hypercalcemic effect. Topical treatment with calcipotriene has been shown to be effective, well tolerated, and safe for psoriasis.
维生素D3的天然形式，即1,25 - 二羟基维生素D3，可调节表皮增殖和分化，并抑制免疫诱导。卡泊三醇（钙泊三烯）是一种合成维生素D类似物，它能将新发现的作用与经典的高钙血症作用部分区分开来。已证明外用钙泊三烯对银屑病有效、耐受性良好且安全。
