Hosoda M, Hashimoto H, He F, Morita H, Hosono A
Technical Research Laboratory, Takanashi Milk Products Co., Ltd, Yokohama, Japan.
J Dairy Sci. 1996 May;79(5):745-9. doi: 10.3168/jds.S0022-0302(96)76421-4.
To demonstrate the antimutagenic effect of fermented milk in the human intestine, fecal mutagenicity and bacterial composition of six healthy subjects consuming their regular diet were investigated before and during the administration of milk fermented with Lactobacillus acidophilus LA-2. The administration of the fermented milk caused a remarkable decrease (71.9% on the average; range of 19.4 to 90.6%) in fecal mutagenicity compared with that before the administration; Lactobacillus spp. and Bifidobacterium spp. population increased in the feces of all subjects. The suppression of fecal mutagenicity appeared to be due to the change in fecal microflora caused by the presence of strain LA-2 in the human intestine.
为了证明发酵乳在人体肠道中的抗诱变作用，在六名食用常规饮食的健康受试者服用嗜酸乳杆菌LA - 2发酵乳之前和期间，对其粪便诱变性和细菌组成进行了研究。与服用前相比，服用发酵乳后粪便诱变性显著降低（平均降低71.9%；范围为19.4%至90.6%）；所有受试者粪便中的乳酸杆菌属和双歧杆菌属数量均增加。粪便诱变性的抑制似乎是由于人体肠道中存在LA - 2菌株导致粪便微生物群发生变化所致。
