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婴儿喂养史显示瑞典乳糜泻患儿与对照儿童之间存在明显差异。

Infant feeding history shows distinct differences between Swedish celiac and reference children.

作者信息

Fälth-Magnusson K, Franzén L, Jansson G, Laurin P, Stenhammar L

机构信息

Department of Pediatrics, Faculty of Health Sciences, Linköping University, Sweden.

出版信息

Pediatr Allergy Immunol. 1996 Feb;7(1):1-5. doi: 10.1111/j.1399-3038.1996.tb00098.x.

DOI:10.1111/j.1399-3038.1996.tb00098.x
PMID:8792377
Abstract

Infant feeding history was investigated in 72 celiac and 288 age-matched reference children in a retrospective questionnaire study. The reply rate was 100% in celiac and 91.6% in reference children. The celiac children were breast-fed for a significantly shorter time than reference children, and they were less often breast-fed at the introduction of gluten. The age of the children at gluten introduction was similar, but the celiac children were significantly more often introduced by a gluten-containing follow-up formula, while the reference children more often started on a gluten-containing porridge. The results can be interpreted in two ways. First, it could be argued that breast milk per se protects against symptoms of celiac disease in childhood. It could, however, also be claimed that breast-feeding merely modulates the gluten introduction, causing a less abrupt introduction of gluten in the baby diet and thereby fewer overt symptoms of the disease.

摘要

在一项回顾性问卷调查研究中,对72名乳糜泻患儿和288名年龄匹配的对照儿童的婴儿喂养史进行了调查。乳糜泻患儿的回复率为100%,对照儿童的回复率为91.6%。乳糜泻患儿的母乳喂养时间明显短于对照儿童,在引入麸质时进行母乳喂养的频率也较低。引入麸质时儿童的年龄相似,但乳糜泻患儿使用含麸质后续配方奶粉引入麸质的频率明显更高,而对照儿童更多是从含麸质粥开始。这些结果可以有两种解释。首先,可以认为母乳本身可预防儿童期乳糜泻症状。然而,也可以声称母乳喂养只是调节了麸质的引入,使婴儿饮食中麸质的引入不那么突然,从而减少了该疾病的明显症状。

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