Greco P, Loverro G, Vimercati A, Marzullo A, Caruso G, Selvaggi L
Cattedra di Patologia Ostetrica e Ginecologica R, Università di Bari, Italy.
Prenat Diagn. 1996 Jun;16(6):503-9. doi: 10.1002/(SICI)1097-0223(199606)16:6<503::AID-PD902>3.0.CO;2-F.
The pathological mechanism that causes the transient phenomenon sonographically defined as "nuchal translucency' is still poorly understood. Seven pregnancies in which the fetuses clearly presented this ultrasonic sign at 10-14 weeks' gestation were terminated because of an abnormal fetal karyotype. The pathological specimens, compared by morphometric analysis with normal fetuses of the same gestational age, showed oedema and dilatation of lymphatic capillary vessels. No particular relationship was found with any structural abnormality. We speculate that nuchal oedema is a transient non-specific phenomenon which is probably related to an early disarrangement of lymphatic connections.
超声检查中定义为“颈部半透明”的短暂现象的病理机制仍知之甚少。7例妊娠在孕10 - 14周时胎儿明显出现这种超声征象，因胎儿染色体核型异常而终止妊娠。病理标本经形态计量分析与相同孕周的正常胎儿比较，显示淋巴管毛细血管水肿和扩张。未发现与任何结构异常有特定关系。我们推测颈部水肿是一种短暂的非特异性现象，可能与淋巴连接的早期紊乱有关。
