Kayser F H
Infection. 1977;5(2):123-5.
Adenylylating or acetylating enzymes, which are produced by grampositive and gramnegative bacteria resistant to aminoglycoside antibiotics, are useful tools in determining concentrations of aminoglycosides in patients' body fluids. Due to their accuracy, stability, versatility, fastness and inexpensiveness, enzymatic assays are the tests of choice for the routine determination of aminoglycoside concentrations.
由对氨基糖苷类抗生素耐药的革兰氏阳性菌和革兰氏阴性菌产生的腺苷酸化酶或乙酰化酶,是测定患者体液中氨基糖苷类药物浓度的有用工具。由于其准确性、稳定性、通用性、快速性和低成本,酶法测定是常规测定氨基糖苷类药物浓度的首选检测方法。