Yoshikawa M, Murakami T, Kadoya M, Matsuda H, Muraoka O, Yamahara J, Murakami N
Kyoto Pharmaceutical University, Japan.
Chem Pharm Bull (Tokyo). 1996 Jun;44(6):1212-7. doi: 10.1248/cpb.44.1212.
Betavulgarosides I, II, III, and IV, oleanolic acid oligoglycosides having an unique acidic substituent, were isolated from the root of Beta vulgaris L. (sugar beet) together with betavulgarosides VI, VII, and VIII. The chemical structures of betavulgarosides I, II, III, IV were identified from chemical and physicochemical evidence. Betavulgarosides II, III, and IV were found to exhibit hypoglycemic activity in an oral glucose tolerance test in rats.
从甜菜(Beta vulgaris L.)根部分离出了具有独特酸性取代基的齐墩果酸寡糖苷β- vulgarosides I、II、III和IV,同时还分离出了β- vulgarosides VI、VII和VIII。通过化学和物理化学证据确定了β- vulgarosides I、II、III、IV的化学结构。在大鼠口服葡萄糖耐量试验中,发现β- vulgarosides II、III和IV具有降血糖活性。