Medentsev A G, Akimenko V K
Mikrobiologiia. 1977 Mar-Apr;46(2):197-202.
The effect of rotenone, antimycin A, oligomycin, 2,4,-DNP, and various subtrates on the appearance of cyanide-resistant respiration of Candida lipolytica yeast was studied. Rotenone inhibited the development of cyanide-resistant respiration, but did not prevent its origination. Antimycin A and oligomycin increased the rate of the appearance of cyanide-resistant respiration. If the resting yeast culture was incubated with 2,4-DNP, glucose, or glycerol, the development of the alternative pathway of electron transport was inhibited. Such substrates as alpha-glycerophosphate, citrate, and D,L-lactate had no effect on the time of appearance of cyanide-resistant respiration. Therefore, in the stationary growth phase, an alternative, cyanide-resistant pathway of electron transport results from the inhibition of the rate of electron transport in the respiration chain.
研究了鱼藤酮、抗霉素A、寡霉素、2,4-二硝基苯酚（2,4-DNP）和各种底物对解脂假丝酵母酵母抗氰呼吸出现的影响。鱼藤酮抑制抗氰呼吸的发展，但不阻止其产生。抗霉素A和寡霉素提高了抗氰呼吸出现的速率。如果将静止的酵母培养物与2,4-DNP、葡萄糖或甘油一起孵育，电子传递替代途径的发展会受到抑制。诸如α-甘油磷酸、柠檬酸盐和D,L-乳酸等底物对抗氰呼吸出现的时间没有影响。因此，在稳定生长阶段，电子传递的替代抗氰途径是由于呼吸链中电子传递速率受到抑制而产生的。
