Mantzoros C S, Evagelopoulou K, Georgiadis E I, Katsilambros N
Endocrine Unit 401 Military Hospital, Athens, Greece.
Horm Metab Res. 1996 Jan;28(1):32-4. doi: 10.1055/s-2007-979126.
Conicity index (C index), an index of abdominal obesity that was developed based on a model of geometric reasoning, proved to be a sensitive and better than the waist to hip ratio indicator of risk for hyperlipidemia in Western populations. To evaluate comparatively the C index and the Waist-to-Hip Ratio (WHR) as predictors of blood pressure levels, insulin and triglyceride concentrations, we performed a cross-sectional study on 280 healthy women, 18-24 year-old. C index was found to be within the expected range (0.95 to 1.73) and significantly correlated with WHR (r = 0.562, p = 0.0001) and body weight (r = 0.312, p = 0.0001). Additionally, C index correlated with fasting insulin levels (r = 0.13, p = 0.03), and systolic blood pressure (r = 0.14, p = 0.02). WHR correlated with fasting insulin levels (r = 0.12, p = 0.05), systolic blood pressure (r = 0.12, p = 0.13) and triglycerides (r = 0.22, p = 0.0006). C index and WHR are equally good, albeit weak, predictors of fasting insulin and blood pressure levels, while WHR proved to be a better than C index predictor of triglyceride concentrations in this population of healthy premenopausal Greek women. Further epidemiologic studies to comparatively evaluate the two indexes as predictors of risk for the development of metabolic disorders and cardiovascular disease in various populations are needed.
锥度指数（C指数）是一种基于几何推理模型开发的腹部肥胖指标，在西方人群中，它被证明是一种比腰臀比更敏感、更好的高脂血症风险指标。为了比较评估C指数和腰臀比（WHR）作为血压水平、胰岛素和甘油三酯浓度预测指标的情况，我们对280名年龄在18至24岁的健康女性进行了一项横断面研究。结果发现C指数在预期范围内（0.95至1.73），且与WHR（r = 0.562，p = 0.0001）和体重（r = 0.312，p = 0.0001）显著相关。此外，C指数与空腹胰岛素水平（r = 0.13，p = 0.03）和收缩压（r = 0.14，p = 0.02）相关。WHR与空腹胰岛素水平（r = 0.12，p = 0.05）、收缩压（r = 0.12，p = 0.13）和甘油三酯（r = 0.22，p = 0.0006）相关。在这群健康的希腊绝经前女性中，C指数和WHR在预测空腹胰岛素和血压水平方面同样有效，尽管关联较弱，而WHR在预测甘油三酯浓度方面被证明比C指数更好。需要进一步开展流行病学研究，以比较评估这两个指标作为不同人群代谢紊乱和心血管疾病发生风险预测指标的情况。
