Collier J F, Maguire S, McGing P, Codd M B, Kyne F, Wright E, Halton K, UaConaill D, Sugrue D D
Department of Biochemistry, Mater Misericordiae Hospital, Dublin.
Ir J Med Sci. 1996 Jul-Sep;165(3):177-81. doi: 10.1007/BF02940246.
Serum samples from 954 Irish adults (604 males, 350 females) aged 18 to 65 years were analyzed within 24 hours of receipt for non-fasting total serum cholesterol levels. The subjects were volunteer blood donors (Blood Transfusion Service Board, Pelican House, Dublin) presenting from June 1990 to February 1991. Serum cholesterol increased significantly with age in both males and females. Mean serum cholesterol in males increased from 4.5 (+/- 0.9) mmol/l in those < 25 years, to 5.7 (+/- 1.0) mmol/l at age 55-64 years. In females, mean serum cholesterol increased from 4.3 (+/- 0.9) mmol/l less than 25 years to 6.2 (+/- 0.8) mmol/l at age 55-64 years. Options for reporting cholesterol ranges are discussed. The overall mean cholesterol concentration of 5.1 mmol/l seen in this study is lower than that reported for comparable studies of U.K. and American subjects, but higher than observed in Japanese individuals. Almost 48% of the studied population had a serum cholesterol value less than 5 mmol/l and over 56% had levels less than 5.2 mmol/l.
对954名年龄在18至65岁之间的爱尔兰成年人（604名男性，350名女性）的血清样本在收到后24小时内进行分析，以检测非空腹血清总胆固醇水平。这些受试者是1990年6月至1991年2月期间前来献血的志愿者（都柏林佩利肯大厦输血服务委员会）。男性和女性的血清胆固醇均随年龄显著增加。男性的平均血清胆固醇从25岁以下人群的4.5（±0.9）mmol/l增加到55至64岁人群的5.7（±1.0）mmol/l。在女性中，平均血清胆固醇从25岁以下的4.3（±0.9）mmol/l增加到55至64岁的6.2（±0.8）mmol/l。讨论了报告胆固醇范围的选项。本研究中观察到的总体平均胆固醇浓度为5.1 mmol/l，低于英国和美国受试者的类似研究报告值，但高于日本人群的观察值。近48%的研究人群血清胆固醇值低于5 mmol/l，超过56%的人胆固醇水平低于5.2 mmol/l。
