鼠冠状病毒作为神经组织中病毒蛋白运输与组装的模型。
The murine coronavirus as a model of trafficking and assembly of viral proteins in neural tissue.
作者信息
Kalicharran K, Dales S
机构信息
Dept of Microbiology and Immunology, University of Western Ontario, London, Canada.
出版信息
Trends Microbiol. 1996 Jul;4(7):264-9. doi: 10.1016/0966-842x(96)10045-7.
Abstract
The replication of JHM, a murine coronavirus, provides a useful model of the assembly and dissemination of viral components in neuronal cells. Involvement of microtubules in virus trafficking is an important feature which may explain dissemination of the infection from primary cell targets at olfactory, hippocampal and cerebellar sites within the central nervous system, resulting in severe neuropathies.
摘要
鼠冠状病毒JHM的复制为病毒成分在神经元细胞中的组装和传播提供了一个有用的模型。微管参与病毒运输是一个重要特征，这可能解释了感染如何从中枢神经系统内嗅觉、海马和小脑部位的主要细胞靶点传播，从而导致严重的神经病变。
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本文引用的文献
1
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2
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J Neurosci. 1993 Jun;13(6):2515-39. doi: 10.1523/JNEUROSCI.13-06-02515.1993.
3
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Neuroscience. 1993 Dec;57(4):1007-25. doi: 10.1016/0306-4522(93)90045-h.
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