Zimhony O, Sthoeger Z, Ben David D, Bar Khayim Y, Geltner D
Department of Internal Medicine C, Kaplan Hospital, Rehovot, Israel.
J Rheumatol. 1995 Dec;22(12):2366-8.
A 57-year-old woman presented with a flaccid paralysis, muscle tenderness, and respiratory depression. Laboratory results demonstrated severe hypokalemia with hyperchloremic metabolic acidosis and abnormally acidified urine. The urinary anion gap was positive in the presence of acidemia, thus establishing the diagnosis of distal renal tubular acidosis (DRTA). The patient fully recovered after potassium and alkali replacement. Further investigation revealed Sjögren's syndrome as the underlying cause of DRTA.
一名57岁女性出现弛缓性麻痹、肌肉压痛和呼吸抑制。实验室检查结果显示严重低钾血症伴高氯性代谢性酸中毒及尿液异常酸化。在存在酸血症的情况下,尿阴离子间隙为阳性,从而确诊为远端肾小管酸中毒(DRTA)。经补钾和补碱治疗后,患者完全康复。进一步检查发现干燥综合征是DRTA的潜在病因。