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Distribution of the HLA-DQA1 polymorphism in the population of the Basque Country (Spain).

作者信息

Esparza B, Pestoni C, Martin M D, Merino F, Carracedo A

机构信息

Facultad de Medicina y Odontología, Universidad del País Vasco, Leioa, Vizcaya, Spain.

出版信息

Gene Geogr. 1995 Apr;9(1):53-8.

PMID:8845339
Abstract

Allele and genotype frequencies at the HLA-DQA1 locus were determined in Basque Country populations using PCR methodology and a dot-blot assay with ASO probes. The results showed no deviation from the Hardy-Weinberg equilibrium. No differences were found between the three Basque Provinces, but gene frequencies were significantly different from those of some other Spanish and world populations.

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