Gjone H, Nøvik T S
National Centre for Child and Adolescent Psychiatry, University of Oslo, Norway.
J Child Psychol Psychiatry. 1995 Oct;36(7):1213-24. doi: 10.1111/j.1469-7610.1995.tb01366.x.
Generalization from twin studies relies on the assumption that liability to develop the disorder which is studied is influenced by similar factors in twins and singletons. The present study examines the impact of pre- and perinatal factors on parental reports of behaviour problems in 1832 twins, and compares level of attention problems, internalizing and externalizing behaviour in the twins with 723 children and adolescents from a general population sample. The modest influence of relative birth weight and birth order on level of attention problems in twins did not contribute to significant differences between twins and the general population sample. The levels of attention problems and externalizing behaviour was similar and there was a modest age dependent difference in internalizing behaviour. An increased variance was found for externalizing behaviour in twins.
双胞胎研究的推广依赖于这样一种假设，即患所研究疾病的易感性受到双胞胎和单胎中相似因素的影响。本研究考察了产前和围产期因素对1832对双胞胎父母报告的行为问题的影响，并将双胞胎中注意力问题、内化行为和外化行为的水平与来自普通人群样本的723名儿童和青少年进行了比较。相对出生体重和出生顺序对双胞胎注意力问题水平的适度影响并未导致双胞胎与普通人群样本之间的显著差异。注意力问题和外化行为的水平相似，内化行为存在适度的年龄依赖性差异。发现双胞胎中外化行为的方差增加。
