Nakao K, Ohba N
Department of Ophthalmology, Kagoshima University Faculty of Medicine.
Nippon Ganka Gakkai Zasshi. 1996 Feb;100(2):150-5.
To estimate the current trend in prevalence of endogenous uveitis and HTLV-I-associated uveitis (HAU) in a local area, we sent questionnaires to all ophthalmologic clinics in Kagoshima Prefecture, southern Japan, which has a population of 1.8 million, with reference to uveitis patients seen during May-July 1993 and May-June 1994. Answers to the questionnaires were obtained from about half of the ophthalmologists in each survey session. The proportion of uveitis cases was on the average 0.4% of outpatients, and the prevalence of uveitis was estimated to be 40.4 x 10(-5). The major uveitis entity consisted of toxoplasmosis (7.8%), Vogt-Koyanagi-Harada disease (5.0%), Behçet's disease (4.1%), sarcoidosis (3.4%), and 71.3% of unclassified cases. An additional study for the infection with HTLV-I revealed that the seropositivity for anti-HTLV-I antibodies was 11 (17.5%) of 63 patients with distinct uveitis entities and 38 (30.4%) of 125 patients with etiologically undefined uveitis, indicating no significant difference in HTLV-I infection between the two groups. The prevalence of HAU was estimated to be 8.8 x 10(-5).
为评估当地内源性葡萄膜炎和人类T淋巴细胞病毒I型相关葡萄膜炎（HAU）的流行趋势，我们向日本南部鹿儿岛县的所有眼科诊所发放了问卷，该县人口为180万，问卷涉及1993年5月至7月以及1994年5月至6月期间诊治的葡萄膜炎患者。每次调查中约半数眼科医生回复了问卷。葡萄膜炎病例占门诊患者的比例平均为0.4%，葡萄膜炎患病率估计为40.4×10⁻⁵。主要的葡萄膜炎类型包括弓形虫病（7.8%）、伏格特-小柳-原田病（5.0%）、白塞病（4.1%）、结节病（3.4%），未分类病例占71.3%。一项关于人类T淋巴细胞病毒I型感染的补充研究显示，63例明确葡萄膜炎类型患者中抗人类T淋巴细胞病毒I型抗体血清阳性率为11例（17.5%），125例病因不明葡萄膜炎患者中为38例（30.4%），表明两组在人类T淋巴细胞病毒I型感染方面无显著差异。HAU患病率估计为8.8×10⁻⁵。
