• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一例非典型银屑病性脊柱炎病例,采用甲氨蝶呤治疗成功。

An atypical psoriatic spondylitis case, successfully treated with methotrexate.

作者信息

Tüzün C, Peker O, Küçüktaş F, Gülbahar S, Kovanlikaya I, Füzün S

机构信息

Dokuz Eylül University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Izmir, Turkey.

出版信息

Clin Rheumatol. 1996 Jul;15(4):403-9. doi: 10.1007/BF02230367.

DOI:10.1007/BF02230367
PMID:8853178
Abstract

We present a 45-year-old male patient who was hospitalized with lumbar disc herniation and whose control magnetic resonance imaging (MRI) findings initially suggested brucella spondylitis. Definitive diagnosis, however, indicated psoriatic spondylitis and the patient was successfully treated with methotrexate. A diagnosis of lumbar disc herniation was made in May 1991, during his psoriasis vulgaris treatment. He was hospitalized in August 1994 with a complaint of low-back pain persisting over the last six months despite treatment with analgesics. He was evaluated by clinical, radiological, laboratory and scintigraphic methods, following control MRI findings suggesting infection of vertebral bodies, particularly pointing to brucellosis in addition to disc herniation. A diagnosis of psoriatic spondylitis was finally established and 7.5 mg methotrexate weekly was administered. Significant improvement was obtained of psoriatic skin lesions, low-back pain and MRI findings through a six-month treatment period.

摘要

我们报告一名45岁男性患者,因腰椎间盘突出症入院,其对照磁共振成像(MRI)结果最初提示布鲁氏菌性脊柱炎。然而,最终诊断为银屑病性脊柱炎,该患者接受甲氨蝶呤治疗后成功康复。1991年5月,在他寻常型银屑病治疗期间诊断出腰椎间盘突出症。1994年8月,他因尽管使用了镇痛药但仍持续背痛六个月而入院。在对照MRI结果提示椎体感染,特别是除椎间盘突出症外还指向布鲁氏菌病后,通过临床、放射学、实验室和闪烁扫描法对他进行了评估。最终确诊为银屑病性脊柱炎,并每周给予7.5毫克甲氨蝶呤。经过六个月的治疗期,银屑病皮肤病变、腰痛和MRI结果均有显著改善。

相似文献

1
An atypical psoriatic spondylitis case, successfully treated with methotrexate.一例非典型银屑病性脊柱炎病例,采用甲氨蝶呤治疗成功。
Clin Rheumatol. 1996 Jul;15(4):403-9. doi: 10.1007/BF02230367.
2
Spondylitic psoriatic arthritis presenting as acute urinary retention.以急性尿潴留为表现的脊柱关节病型银屑病关节炎。
BMJ Case Rep. 2014 Apr 30;2014:bcr2013202383. doi: 10.1136/bcr-2013-202383.
3
Brucella spondylitis. A brief review and case report.布鲁氏菌性脊柱炎。简要综述及病例报告。
Clin Orthop Relat Res. 1972 Jan-Feb;82:87-91.
4
Anterior disc protrusion as a cause for abdominal symptoms in childhood discitis. A case report.儿童椎间盘炎中前侧椎间盘突出作为腹部症状的病因:一例报告。
Spine (Phila Pa 1976). 1999 May 1;24(9):918-20. doi: 10.1097/00007632-199905010-00016.
5
Do Biologic-treated Psoriatic Arthritis Patients with Spondylitis Respond Differently with or without Concomitant Methotrexate from Patients without Spondylitis?接受生物制剂治疗的银屑病关节炎合并脊柱炎患者与未合并脊柱炎患者相比,在联合或不联合甲氨蝶呤治疗时反应是否不同?
J Rheumatol. 2016 Mar;43(3):471-3. doi: 10.3899/jrheum.160046.
6
Assessment and treatment of psoriatic spondylitis.银屑病关节炎的评估与治疗。
Curr Rheumatol Rep. 2009 Aug;11(4):278-83. doi: 10.1007/s11926-009-0039-8.
7
Spondylodiscitis as the only clinical manifestation of the onset of psoriatic spondyloarthritis.脊椎间盘炎作为银屑病性脊柱关节炎发病的唯一临床表现。
Reumatismo. 2011 Mar;63(1):38-43. doi: 10.4081/reumatismo.2011.38.
8
[Lumbar disc herniation].[腰椎间盘突出症]
Chir Narzadow Ruchu Ortop Pol. 2007 Mar-Apr;72(2):95-7.
9
Multidisciplinary focus on methotrexate in psoriatic disesase.银屑病中氨甲蝶呤的多学科研究重点。
J Rheumatol Suppl. 2009 Aug;83:56-8. doi: 10.3899/jrheum.090226.
10
Real-time polymerase chain reaction detection and surgical treatment of thoracic and lumbar spondylitis due to infection: two typical case reports.实时聚合酶链反应检测与感染性胸腰椎炎的手术治疗:两典型病例报告。
Front Public Health. 2024 May 22;12:1396152. doi: 10.3389/fpubh.2024.1396152. eCollection 2024.

引用本文的文献

1
MRI in psoriatic arthritis: insights into pathogenesis and treatment response.银屑病关节炎的磁共振成像:对发病机制和治疗反应的见解
Curr Rheumatol Rep. 2008 Aug;10(4):303-10. doi: 10.1007/s11926-008-0049-y.
2
Magnetic resonance imaging in psoriatic arthritis: a review of the literature.银屑病关节炎的磁共振成像:文献综述
Arthritis Res Ther. 2006;8(2):207. doi: 10.1186/ar1934. Epub 2006 Mar 23.

本文引用的文献

1
Ankylosing spondylitis successfully treated with methotrexate.甲氨蝶呤成功治疗强直性脊柱炎。
Intern Med. 1993 Jan;32(1):53-6. doi: 10.2169/internalmedicine.32.53.
2
[Psoriasis arthropathica].[关节病型银屑病]
Ann Dermatol Venereol. 1993;120(1):5-13.
3
Brucellosis of the spine.
Neurosurgery. 1993 Nov;33(5):838-44. doi: 10.1227/00006123-199311000-00008.
4
Methotrexate in psoriatic polyarthritis.甲氨蝶呤用于银屑病性多关节炎。
Acta Derm Venereol Suppl (Stockh). 1994;186:114-5.
5
Methotrexate in psoriatic arthritis: a retrospective study.甲氨蝶呤治疗银屑病关节炎:一项回顾性研究。
Acta Derm Venereol. 1983;63(2):165-7.
6
Articular involvement in human brucellosis: a retrospective analysis of 304 cases.人类布鲁氏菌病的关节受累情况:304例回顾性分析
Semin Arthritis Rheum. 1982 Nov;12(2):245-55. doi: 10.1016/0049-0172(82)90064-6.
7
Association between rheumatoid arthritis and psoriasis in total populations.总体人群中类风湿关节炎与银屑病之间的关联。
Acta Rheumatol Scand. 1969;15(4):316-26. doi: 10.3109/rhe1.1969.15.issue-1-4.40.
8
Lumbar herniated disk disease and canal stenosis: prospective evaluation by surface coil MR, CT, and myelography.腰椎间盘突出症和椎管狭窄:表面线圈磁共振成像、计算机断层扫描和脊髓造影的前瞻性评估
AJR Am J Roentgenol. 1986 Oct;147(4):757-65. doi: 10.2214/ajr.147.4.757.
9
CT/MR spectrum of far lateral and anterior lumbosacral disk herniations.腰骶部远外侧和前位椎间盘突出症的CT/MR影像特征
AJNR Am J Neuroradiol. 1988 Jul-Aug;9(4):775-8.
10
Tears of the anulus fibrosus: correlation between MR and pathologic findings in cadavers.纤维环撕裂:尸体中磁共振成像(MR)与病理结果的相关性
AJNR Am J Neuroradiol. 1988 Mar-Apr;9(2):367-70.