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一例非典型银屑病性脊柱炎病例,采用甲氨蝶呤治疗成功。

An atypical psoriatic spondylitis case, successfully treated with methotrexate.

作者信息

Tüzün C, Peker O, Küçüktaş F, Gülbahar S, Kovanlikaya I, Füzün S

机构信息

Dokuz Eylül University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Izmir, Turkey.

出版信息

Clin Rheumatol. 1996 Jul;15(4):403-9. doi: 10.1007/BF02230367.

Abstract

We present a 45-year-old male patient who was hospitalized with lumbar disc herniation and whose control magnetic resonance imaging (MRI) findings initially suggested brucella spondylitis. Definitive diagnosis, however, indicated psoriatic spondylitis and the patient was successfully treated with methotrexate. A diagnosis of lumbar disc herniation was made in May 1991, during his psoriasis vulgaris treatment. He was hospitalized in August 1994 with a complaint of low-back pain persisting over the last six months despite treatment with analgesics. He was evaluated by clinical, radiological, laboratory and scintigraphic methods, following control MRI findings suggesting infection of vertebral bodies, particularly pointing to brucellosis in addition to disc herniation. A diagnosis of psoriatic spondylitis was finally established and 7.5 mg methotrexate weekly was administered. Significant improvement was obtained of psoriatic skin lesions, low-back pain and MRI findings through a six-month treatment period.

摘要

我们报告一名45岁男性患者,因腰椎间盘突出症入院,其对照磁共振成像(MRI)结果最初提示布鲁氏菌性脊柱炎。然而,最终诊断为银屑病性脊柱炎,该患者接受甲氨蝶呤治疗后成功康复。1991年5月,在他寻常型银屑病治疗期间诊断出腰椎间盘突出症。1994年8月,他因尽管使用了镇痛药但仍持续背痛六个月而入院。在对照MRI结果提示椎体感染,特别是除椎间盘突出症外还指向布鲁氏菌病后,通过临床、放射学、实验室和闪烁扫描法对他进行了评估。最终确诊为银屑病性脊柱炎,并每周给予7.5毫克甲氨蝶呤。经过六个月的治疗期,银屑病皮肤病变、腰痛和MRI结果均有显著改善。

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