Strüder H K, Hollmann W, Platen P
Institute of Sports Games, German Sport University, Cologne, Germany.
Int J Sports Med. 1996 Jul;17(5):390-2. doi: 10.1055/s-2007-972866.
Neuroendocrine responses were investigated in 8 male athletes before, during and after 60 min of bicycle ergometry at an intensity corresponding to 1.5 mmol/l blood lactate in an incremental bicycle test. Hyperoxic gas (HE: 100% O2), hypoxic gas (HO: 14% O2, 86% N2) or normoxic gas (NO) were inhaled continuously during exercise as well as for 30 min before and after. During exercise, prolactin (PRL) increased in HO while it did not change significantly in NO. Only HE induced a PRL increase (400%) during 30 min of rest before exercise. PRL decreased in HE during exercise but remained higher than in HO. Growth hormone (GH), ACTH and norepinephrine (NE) did not increase in a similar pattern during HE. In comparison to NO and HE, increase of NE, GH and ACTH was significantly higher in HO, NE declined significantly in HE before exercise. Our results demonstrate that only PRL is affected by acute exposure to hyperoxia. Changes in inhibition of the dopaminergic system might contribute to augmentation of PRL before exercise. The exact underlying mechanisms are yet unknown.
在递增式自行车测试中，以对应于1.5毫摩尔/升血乳酸的强度，对8名男性运动员在60分钟自行车测力计运动前、运动中和运动后进行了神经内分泌反应研究。在运动期间以及运动前和运动后30分钟持续吸入高氧气体（HE：100% O₂）、低氧气体（HO：14% O₂，86% N₂）或常氧气体（NO）。运动期间，HO组催乳素（PRL）升高，而NO组无显著变化。仅HE在运动前30分钟休息期间诱导PRL升高（400%）。运动期间HE组PRL下降，但仍高于HO组。运动期间HE组生长激素（GH）、促肾上腺皮质激素（ACTH）和去甲肾上腺素（NE）未以类似模式增加。与NO和HE相比，HO组NE、GH和ACTH的增加显著更高，运动前HE组NE显著下降。我们的结果表明，只有PRL受急性高氧暴露影响。多巴胺能系统抑制的变化可能有助于运动前PRL的增加。确切的潜在机制尚不清楚。
