Raitta C, Tomita G, Vesti E, Harju M, Nakao H
Department of Ophthalmology, University of Helsinki, Finland.
Ophthalmic Surg Lasers. 1996 May;27(5):349-54.
To analyze changes in the optic disc topography after filtration surgery.
Laser scanning tomography was performed in 10 eyes of 9 patients (mean age 65.6 +/- 8.1 years; age range 55 to 75 years) after a mean follow-up of 3.7 months, and in 8 eyes of 7 patients (mean age 63.1 +/- 7.6 years; age range 55 to 75 years) after a mean follow-up of 13.1 months.
Preoperatively, the mean intraocular pressure (IOP) was 24.4 +/- 6.9 mm Hg with maximal medication. Postoperatively at 3.7 months it was 11.0 +/- 2.2 mm Hg, and at l2.1 months it was l3.6 +/- 2.8 mm Hg. An initial reduction in IOP of more than 30 percent at 3.7 months was achieved without medication in all but 1 eye. After 12.1 months, an IOP reduction of more than 30 percent was achieved in 6 of 8 eyes (1 with medication), while 2 eyes had IOP reductions of less than 15 percent (< or = 3 mm Hg) despite medication. In the 6 eyes, the optic disc cup volume showed a decrease of more than 30 percent, while the 2 eyes without marked IOP reductions had slight increases in cup volume. Of the 2 eyes without marked decreases in cup size, 1 had normal-tension glaucoma and 1 experienced an increase in IOP of more than 25 mm Hg during the first postoperative week.
The postoperative IOP should be kept low enough to permit reversal of optic disc changes.
分析滤过性手术后视盘地形图的变化。
对9例患者的10只眼(平均年龄65.6±8.1岁;年龄范围55至75岁)进行了平均3.7个月的随访后行激光扫描断层扫描,以及对7例患者的8只眼(平均年龄63.1±7.6岁;年龄范围55至75岁)进行了平均13.1个月的随访后行激光扫描断层扫描。
术前,最大药物治疗下平均眼压(IOP)为24.4±6.9 mmHg。术后3.7个月时为11.0±2.2 mmHg,12.1个月时为13.6±2.8 mmHg。除1只眼外,所有眼睛在3.7个月时无需药物治疗眼压初始降低超过30%。12.1个月后,8只眼中有6只(1只使用药物)眼压降低超过30%,而2只眼尽管使用药物眼压降低仍小于15%(≤3 mmHg)。在这6只眼中,视盘杯状容积减少超过30%,而2只眼压未显著降低的眼睛杯状容积略有增加。在杯状大小未显著减小的2只眼中,1只患有正常眼压性青光眼,1只在术后第一周眼压升高超过25 mmHg。
术后眼压应保持足够低,以促使视盘变化逆转。