Eppright T D, Sanfacon J A, Horwitz E A
Deparment of Psychiatry and Neurology, University of Missouri-Columbia, 65212
Mo Med. 1996 Mar;93(3):136-8.
This case involves a 4 1/2-year-old boy diagnosed with autism, attention deficit hyperactivity disorder (ADHD), and an elevated blood-lead level of 42 mcg/dl. The child was treated for the elevated blood-lead with the chelating agent succimer. The parents reported a decrease in repetitive behaviors while on succimer with a regression to previous symptoms when medication was discontinued. Also seen was a decrease of hyperactive behavior while being treated with succimer. This article explores the interaction and possible casual relationship of an elevated blood-lead, autism, and ADHD as well as treatment of the behavioral symptoms.
该病例涉及一名4岁半的男孩，他被诊断患有自闭症、注意力缺陷多动障碍（ADHD），血铅水平升高至42微克/分升。该儿童使用螯合剂二巯基丁二酸治疗血铅升高。父母报告称，在使用二巯基丁二酸治疗期间，重复行为有所减少，但停药后症状又恢复到之前的状态。同时还观察到，在使用二巯基丁二酸治疗期间，多动行为有所减少。本文探讨了血铅升高、自闭症和ADHD之间的相互作用以及可能的因果关系，以及行为症状的治疗方法。
