一种用于心脏组织除颤的生物物理模型。

Keener J P, Panfilov A V

Department of Mathematics, University of Utah, Salt Lake City 84112, USA.

Biophys J. 1996 Sep;71(3):1335-45. doi: 10.1016/S0006-3495(96)79333-5.

We propose a new model for electrical activity of cardiac tissue that incorporates the effects of cellular microstructure. As such, this model provides insight into the mechanism of direct stimulation and defibrillation of cardiac tissue after injection of large currents. To illustrate the usefulness of the model, numerical stimulations are used to show the difference between successful and unsuccessful defibrillation of large pieces of tissue.

我们提出了一种新的心脏组织电活动模型，该模型纳入了细胞微观结构的影响。因此，该模型为注入大电流后心脏组织的直接刺激和除颤机制提供了见解。为了说明该模型的实用性，我们使用数值模拟来展示大块组织成功除颤和未成功除颤之间的差异。