特发性CD4⁺T淋巴细胞减少症中的淋巴细胞亚群多样性
Lymphocyte subset diversity in idiopathic CD4+ T lymphocytopenia.
作者信息
Tassinari P, Deibis L, Bianco N, Echeverría de Pérez G
机构信息
Instituto de Immunología, Facultad de Medicina, Universidad Central de Venezuela, Caracas, Venezuela.
出版信息
Clin Diagn Lab Immunol. 1996 Sep;3(5):611-3. doi: 10.1128/cdli.3.5.611-613.1996.
Abstract
The clinical and public health importance of CD4+ T lymphocytopenia without human immunodeficiency virus infection is still unclear. We describe herein two new human immunodeficiency virus-negative patients with low numbers of peripheral CD4+ T cells and opportunistic infections (cerebral toxoplasmosis and tuberculosis plus extrapulmonary histoplasmosis). The low numbers of CD4+ CD29+ memory cells, the high percentage of gamma delta T-cell receptor cells, and the recovery of CD4+ cells after treatment were remarkable.
摘要
无人类免疫缺陷病毒感染的CD4 + T淋巴细胞减少症的临床和公共卫生重要性仍不清楚。我们在此描述了两名新的人类免疫缺陷病毒阴性患者，他们外周血CD4 + T细胞数量低且伴有机会性感染（脑弓形虫病、结核病加肺外组织胞浆菌病）。CD4 + CD29 + 记忆细胞数量低、γδT细胞受体细胞百分比高以及治疗后CD4 + 细胞的恢复情况显著。
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