Rodgers J, Bland R
Department of Psychiatry, University of Alberta, Edmonton.
Can J Psychiatry. 1996 Sep;41(7):441-5. doi: 10.1177/070674379604100709.
To report the occurrence, type, causes, and management of psychiatric manifestations in multiple sclerosis (MS).
Review of recent, relevant literature.
Psychiatric illness, especially depression, occurs much more frequently than expected in patients with MS, is frequently unrecognized or ignored, and is treatable using standard methods, although patients with MS may be unusually sensitive to side effects of tricyclic antidepressants.
Research is needed to better define the causes of psychiatric syndromes in patients with MS. Those treating MS should increase their awareness of and sensitivity to the likelihood of psychiatric disorder in these patients.
报告多发性硬化症（MS）患者精神症状的发生率、类型、病因及管理。
回顾近期相关文献。
精神疾病，尤其是抑郁症，在MS患者中的发生率比预期高得多，常未被识别或被忽视，且可采用标准方法治疗，尽管MS患者可能对三环类抗抑郁药的副作用异常敏感。
需要开展研究以更好地明确MS患者精神综合征的病因。治疗MS的人员应提高对这些患者发生精神障碍可能性的认识和敏感度。
