Hoffmann J J, Torrance S J, Widehopf R M, Cole J R
J Pharm Sci. 1977 Jun;66(6):883-4. doi: 10.1002/jps.2600660642.
The ethanol extract of Michelia champaca and the petroleum ether extract of Talauma ovata showed activity toward the human epidermoid carcinoma of the nasopharynx test system. The active constituents were sesquiterpene lactones, identified as parthenolide (C15H20O3) and costunolide (C15H20O2). Their identities were proven by elemental analyses, PMR, IR, and mass spectral data, melting-point and mixed melting-point determinations, and comparisons with authentic samples and spectra.
黄兰乙醇提取物和大花八角石油醚提取物对人鼻咽癌测试系统显示出活性。活性成分是倍半萜内酯，鉴定为小白菊内酯（C15H20O3）和木香烯内酯（C15H20O2）。通过元素分析、核磁共振氢谱、红外光谱、质谱数据、熔点和混合熔点测定以及与标准样品和光谱的比较来证明它们的身份。
