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小鼠静脉注射微小隐孢子虫导致血管内凝血。

Intravascular coagulation resulting from intravenous injection of C. parvum in mice.

作者信息

Lampert I A, Jones P D, Sadler T E, Castro J E

出版信息

Br J Cancer. 1977 Jul;36(1):15-22. doi: 10.1038/bjc.1977.149.

DOI:10.1038/bjc.1977.149
PMID:889682
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2025445/
Abstract

In mice, i.v. C. parvum induces intravascular coagulation. This is a prolonged reaction lasting up to 7 days. It results in thrombosis in hepatic vessels with consequent hepatic necrosis, and thrombosis in pulmonary and splenic vessels. This may be important in the assessment of the tumour-inhibitory activity of C. parvum.

摘要

在小鼠中，静脉注射微小隐孢子虫会引发血管内凝血。这是一种持续长达7天的长期反应。它会导致肝血管血栓形成，进而引发肝坏死，以及肺血管和脾血管血栓形成。这在评估微小隐孢子虫的肿瘤抑制活性方面可能具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a13/2025445/f95f87d392fa/brjcancer00292-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a13/2025445/f95f87d392fa/brjcancer00292-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a13/2025445/f95f87d392fa/brjcancer00292-0029-a.jpg

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1
Intravascular coagulation resulting from intravenous injection of C. parvum in mice.小鼠静脉注射微小隐孢子虫导致血管内凝血。
Br J Cancer. 1977 Jul;36(1):15-22. doi: 10.1038/bjc.1977.149.
2
Histological changes of intravascular coagulation in mice resulting from intravenous injection of C. parvum.静脉注射微小隐孢子虫导致小鼠血管内凝血的组织学变化。
Dev Biol Stand. 1977;38:421-6.
3
Mechanisms of C. Parvum-induced coagulopathy in mice.微小隐孢子虫诱导小鼠凝血病的机制。
Br J Cancer. 1980 Jan;41(1):117-22. doi: 10.1038/bjc.1980.13.
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Intravascular coagulation in the development of massive hepatic necrosis induced by Corynebacterium parvum and endotoxin in rats.微小棒状杆菌和内毒素诱导大鼠发生大量肝坏死过程中的血管内凝血
Scand J Gastroenterol. 1989 Apr;24(3):293-8. doi: 10.3109/00365528909093049.
5
The distribution and persistence in vivo of Corynebacterium parvum in relation to its antitumor activity.短小棒状杆菌在体内的分布及持久性与其抗肿瘤活性的关系
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Radiolabelling of Corynebacterium parvum and its distribution in mice.微小棒状杆菌的放射性标记及其在小鼠体内的分布
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Effects of Corynebacterium parvum on murine myeloid leukaemia.短小棒状杆菌对小鼠髓性白血病的影响。
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Effects of the Landschütz ascites carcinoma and ascitic fluid on macrophage activity in C. parvum-injected mice.
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Effects of intravenous injection of two different strains of Corynebacterium parvum in the mouse.静脉注射两种不同菌株的微小棒状杆菌对小鼠的影响。
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本文引用的文献

1
Inhibitory effect of injection of Corynebacterium parvum on the growth of tumour transplants in isogenic hosts.短小棒状杆菌注射液对同基因宿主肿瘤移植生长的抑制作用。
Br J Cancer. 1966 Jun;20(2):345-55. doi: 10.1038/bjc.1966.42.
2
Mechanisms of release of constituents from rabbit platelets by antigen-antibody complexes and complement. I. Lytic and nonlytic reactions.抗原 - 抗体复合物及补体介导兔血小板成分释放的机制。I. 溶解反应与非溶解反应。
J Immunol. 1970 Aug;105(2):476-89.
3
Experimental tumour metastases and blood coagulability.实验性肿瘤转移与血液凝固性
微小隐孢子虫诱导小鼠凝血病的机制。
Br J Cancer. 1980 Jan;41(1):117-22. doi: 10.1038/bjc.1980.13.
4
Serum biochemical changes in c. parvum-injected mice bearing the Landschütz ascites carcinoma.感染微小隐孢子虫的携带兰施胡茨腹水癌的小鼠的血清生化变化。
Br J Exp Pathol. 1982 Dec;63(6):639-43.
5
Inhibition by the Landschütz ascites carcinoma of the granulomatous inflammatory response to C. parvum.兰施胡茨腹水癌对小隐孢子虫肉芽肿性炎症反应的抑制作用。
Br J Cancer. 1982 Apr;45(4):598-612. doi: 10.1038/bjc.1982.97.
6
Effect of Corynebacterium parvum on peripheral blood platelets.短小棒状杆菌对外周血血小板的影响。
Br J Cancer. 1977 Dec;36(6):777-82. doi: 10.1038/bjc.1977.261.
7
Effects of intravenous injection of two different strains of Corynebacterium parvum in the mouse.静脉注射两种不同菌株的微小棒状杆菌对小鼠的影响。
Br J Exp Pathol. 1979 Dec;60(6):627-31.
8
Protective effect of glucan against systemic Staphylococcus aureus septicemia in normal and leukemic mice.葡聚糖对正常小鼠和白血病小鼠全身性金黄色葡萄球菌败血症的保护作用。
Infect Immun. 1978 Jun;20(3):804-10. doi: 10.1128/iai.20.3.804-810.1978.
9
Effects of Corynebacterium parvum on murine myeloid leukaemia.短小棒状杆菌对小鼠髓性白血病的影响。
Br J Cancer. 1978 Dec;38(6):703-8. doi: 10.1038/bjc.1978.276.
Acta Pathol Microbiol Scand Suppl. 1970;211:Suppl 211:5+.
4
Antimetastatic effects associated with platelet reduction.与血小板减少相关的抗转移作用。
Proc Natl Acad Sci U S A. 1968 Sep;61(1):46-52. doi: 10.1073/pnas.61.1.46.
5
In vitro inhibition of tumour cell growth and DNA synthesis by peritoneal and lung macrophages from mice injected with Corynebacterium parvum.用短小棒状杆菌注射的小鼠腹腔和肺巨噬细胞对肿瘤细胞生长和DNA合成的体外抑制作用
Int J Cancer. 1974 Apr 15;13(4):478-88. doi: 10.1002/ijc.2910130406.
6
Increased phagocytic cell activity and anaemia in Corynebacterium parvum treated mice.用短小棒状杆菌处理的小鼠中吞噬细胞活性增强及贫血现象
Br J Exp Pathol. 1974 Feb;55(1):38-46.
7
Platelet-tumor-cell interactions in mice. The role of platelets in the spread of malignant disease.小鼠体内血小板与肿瘤细胞的相互作用。血小板在恶性疾病扩散中的作用。
Int J Cancer. 1973 May;11(3):704-18. doi: 10.1002/ijc.2910110322.
8
Protection by Corynebacterium parvum against tumour cells injected intravenously.短小棒状杆菌对静脉注射肿瘤细胞的保护作用。
Rev Eur Etud Clin Biol. 1972 May;17(5):498-500.
9
The effect of Corynebacterium parvum on the structure and function of the lymphoid system in mice.短小棒状杆菌对小鼠淋巴系统结构和功能的影响。
Eur J Cancer (1965). 1974 Feb;10(2):115-20. doi: 10.1016/0014-2964(74)90062-0.
10
The behaviour of complement and platelets in lethal endotoxin shock in rabbits.补体和血小板在兔致死性内毒素休克中的行为表现。
Int Arch Allergy Appl Immunol. 1973;45(1):193-205. doi: 10.1159/000231028.