Beals J A, Funk L M, Fountain R, Sedman R
Department of Mathematical Sciences, Portland State University, Portland Oregon 97207, USA.
Environ Health Perspect. 1996 Sep;104(9):974-9. doi: 10.1289/ehp.96104974.
Assessments of inhalation exposure to environmental agents necessitate quantitative estimates of pulmonary ventilation rates. Estimating a range of exposures in a given population requires an understanding of the variability of ventilation rates in the population. Distributions of ventilation rates (Ve) were described based on the results of a large study where Ve were measured while subjects performed a variety of physical tasks. Three distinct ventilation levels were identified using cluster analyses of the mean Ve and then various activities were assigned to the three levels using a k-means procedure. Separate distributions were identified for the three Ve levels for adult males, adult females, and children. The variability of Ve was consistent with a lognormal distribution for all groups. An aggregate daily inhalation rate can be estimated based on the distributions of Ve.
对环境介质吸入暴露的评估需要对肺通气率进行定量估计。估计特定人群中的一系列暴露情况需要了解该人群中通气率的变异性。基于一项大型研究的结果描述了通气率（Ve）的分布情况，在该研究中，当受试者执行各种体力任务时测量了Ve。通过对平均Ve进行聚类分析确定了三个不同的通气水平，然后使用k均值程序将各种活动分配到这三个水平。分别确定了成年男性、成年女性和儿童三个Ve水平的分布。所有组的Ve变异性均符合对数正态分布。可以根据Ve的分布估计每日总吸入率。
