Imrie C W, Ferguson J C, Murphy D, Blumgart L H
Br J Surg. 1977 Mar;64(3):185-8. doi: 10.1002/bjs.1800640310.
Severe arterial hypoxia while breathing ambient air (Pao2 less than 60 mm Hg) was recorded in 38 (45 per cent) of a group of 84 patients with acute pancreatitis when arterial blood gas monitoring was performed during the first week of illness. This contrasted with an incidence of 19 per cent severe hypoxia in a heterogeneous group of 68 patients with acute abdominal pain admitted as surgical emergencies. Clinical evidence of respiratory embarrassment was rarely present in either the patients with acute pancreatitis or the other patients. Arterial hypoxia was related to the prognosis in both groups. It is recommended that all patients with acute pancreatitis have routine arterial blood gas monitoring performed during the first 5 days of illness. Furthermore, all older patients (over 60 years) and younger patients with moderate hypoxia (Pao2 less than 70 mm Hg) should be given supplementary humidified oxygen. An awareness of occult respiratory insufficiency in surgical emergency admissions, and especially in acute pancreatitis, is of importance.
在一组84例急性胰腺炎患者中，于发病第一周进行动脉血气监测时，38例（45%）患者呼吸空气时出现严重动脉低氧血症（动脉血氧分压低于60 mmHg）。相比之下，68例因急性腹痛作为外科急症入院的异质性患者中，严重低氧血症的发生率为19%。急性胰腺炎患者和其他患者很少有呼吸窘迫的临床证据。两组患者的动脉低氧血症均与预后相关。建议所有急性胰腺炎患者在发病的前5天进行常规动脉血气监测。此外，所有老年患者（60岁以上）和中度低氧血症（动脉血氧分压低于70 mmHg）的年轻患者均应给予补充湿化氧气。认识到外科急症入院患者，尤其是急性胰腺炎患者存在隐匿性呼吸功能不全至关重要。
