Uno K, Tsuchida Y, Kawarasaki H
Second Department of Surgery, Teikyo University, Tokyo, Japan.
Nihon Geka Gakkai Zasshi. 1996 Aug;97(8):606-10.
Biliary sricture with dilatation is a putative cause of intrahepatic bile duct stones. However, this hypothesis has never been proven. Fifty-six patients had operative cholangiography, underwent standard excision of a choledochal cyst, and were reviewed at follow-up clinics at a mean follow-up time of 14 years and 6 months. The incidence of complications such as intrahepatic cholelithiasis was analyzed according to the morphologic types of the intrahepatic bile ducts as observed at the initial operation. Group I patients (29 cases) did not show any dilatation of the intrahepatic bile ducts. Only one (3%) developed intrahepatic cholelithiasis. In Group II (24 cases), the intrahepatic bile ducts were dilated but not associated with any down-stream stenosis, one patient (4%) suffered from intrahepatic chalelithasis. Group III patients (3 cases) had dilatation of the intrahepatic bile ducts associated with a down-stream stenosis, and none of them was free from the development of intrahepatic biliary stones (3 cases). Group III patients are most likely to develop intrahepatic cholelithiasis afterwards, and their stenosis should be relieved by whatever means are feasible at initial operation.
伴有扩张的胆管狭窄被认为是肝内胆管结石的一个病因。然而,这一假说从未得到证实。56例患者接受了术中胆管造影,接受了胆总管囊肿的标准切除术,并在随访门诊进行了复查,平均随访时间为14年6个月。根据初次手术时观察到的肝内胆管形态学类型,分析肝内胆石症等并发症的发生率。I组患者(29例)肝内胆管未显示任何扩张。仅1例(3%)发生肝内胆石症。II组(24例)肝内胆管扩张但无任何下游狭窄,1例患者(4%)患有肝内胆石症。III组患者(3例)肝内胆管扩张并伴有下游狭窄,且无一例未发生肝内胆管结石(3例)。III组患者术后最易发生肝内胆石症,应在初次手术时采取任何可行的方法解除其狭窄。