Hartley C, Birzgalis A R, Lyons T J, Farrington W T
University Department of Otolaryngology, University of Manchester Medical School, UK.
J R Coll Surg Edinb. 1996 Oct;41(5):333-5.
Neuroendocrine carcinomas (NEC) of the larynx are rare. The key to diagnosis is therefore an increased awareness of such lesions amongst otolaryngologists and pathologists. A precise histological diagnosis is crucial, as the management is different for each NEC sub-type. Advances in immunohistochemistry have been a great help in this respect. We report a typical case of large cell NEC (atypical carcinoid) and highlight the clinical pointers to the histological diagnosis.
喉神经内分泌癌（NEC）较为罕见。因此，诊断的关键在于提高耳鼻喉科医生和病理学家对此类病变的认识。精确的组织学诊断至关重要，因为每种NEC亚型的治疗方法有所不同。免疫组织化学的进展在这方面提供了很大帮助。我们报告一例典型的大细胞NEC（非典型类癌）病例，并强调组织学诊断的临床要点。
