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通过灌胃给予鱼油可增加大鼠淋巴器官中己糖激酶、葡萄糖-6-磷酸脱氢酶和柠檬酸合酶的活性。

Administration of fish oil by gavage increases the activities of hexokinase, glucose-6-phosphate dehydrogenase, and citrate synthase in rat lymphoid organs.

作者信息

Miyasaka C K, Azevedo R B, Curi R, Mancini Filho J, Lajolo F M

机构信息

Department of Food Sciences, Faculty of Pharmaceutical Sciences, University of São Paulo, Brazil.

出版信息

Gen Pharmacol. 1996 Sep;27(6):991-4. doi: 10.1016/0306-3623(96)00041-9.

DOI:10.1016/0306-3623(96)00041-9
PMID:8909980
Abstract
  1. The effect of administration of fish oil by gavage on key enzyme activities of glucose metabolism of the thymus, spleen, and mesenteric lymph nodes was investigated. 2. The activities of hexokinase, glucose-6-phosphate dehydrogenase, and citrate synthase in the lymphoid organs were markedly raised due to a daily administration of fish oil by gavage (0.4% of body weight). 3. These findings indicate that the therapeutic utilization of fish oil does affect the metabolism of the lymphoid organs, and possibly immune function; however, the mechanism involved remains to be investigated.
摘要
  1. 研究了通过灌胃给予鱼油对胸腺、脾脏和肠系膜淋巴结葡萄糖代谢关键酶活性的影响。2. 由于每天通过灌胃给予鱼油(体重的0.4%),淋巴器官中己糖激酶、葡萄糖-6-磷酸脱氢酶和柠檬酸合酶的活性显著提高。3. 这些发现表明,鱼油的治疗性应用确实会影响淋巴器官的代谢,并可能影响免疫功能;然而,其中涉及的机制仍有待研究。

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Administration of fish oil by gavage increases the activities of hexokinase, glucose-6-phosphate dehydrogenase, and citrate synthase in rat lymphoid organs.通过灌胃给予鱼油可增加大鼠淋巴器官中己糖激酶、葡萄糖-6-磷酸脱氢酶和柠檬酸合酶的活性。
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Polyunsaturated and saturated fatty acids-rich diets and immune tissues. 2. Maximal activities of key enzymes of glutaminolysis, glycolysis, pentose-phosphate-pathway and Krebs cycle in thymus, spleen and mesenteric lymph nodes.
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Effect of the administration of fish oil by gavage on activities of antioxidant enzymes of rat lymphoid organs.通过灌胃给予鱼油对大鼠淋巴器官抗氧化酶活性的影响。
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Effect of mitogens on the maximum activities of hexokinase, lactate dehydrogenase, citrate synthase and glutaminase in rat mesenteric lymph node lymphocytes and splenocytes during the early period of culture.丝裂原对培养早期大鼠肠系膜淋巴结淋巴细胞和脾细胞中己糖激酶、乳酸脱氢酶、柠檬酸合酶和谷氨酰胺酶最大活性的影响。
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