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通过灌胃给予鱼油对大鼠淋巴器官抗氧化酶活性的影响。

Effect of the administration of fish oil by gavage on activities of antioxidant enzymes of rat lymphoid organs.

作者信息

Miyasaka C K, de Souza J A, Torres R P, Filho J M, Lajolo F M, Curi R

机构信息

Department of Nutrition and Food Sciences, Faculty of Pharmaceutical Sciences, University of São Paulo, Brazil.

出版信息

Gen Pharmacol. 1998 May;30(5):759-62. doi: 10.1016/s0306-3623(97)00334-0.

DOI:10.1016/s0306-3623(97)00334-0
PMID:9559331
Abstract
  1. The effect of administration of fish oil by gavage on catalase (CAT), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) activities of the lymphoid organs and liver was compared with those of soybean oil and cocoa butter. 2. Fish oil did not affect the activities of SOD and CAT but reduced that of GSH-Px in the spleen. In contrast, cocoa butter reduced the CAT activity in the thymus and liver, and soybean oil decreased CAT activity in the thymus. 3. The content of thiobarbituric acid reactive substances of the lymphoid organs was not modified but was increased in plasma.
摘要
  1. 将通过灌胃给予鱼油对淋巴器官和肝脏中过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-Px)和超氧化物歧化酶(SOD)活性的影响与大豆油和可可脂的影响进行了比较。2. 鱼油不影响脾脏中SOD和CAT的活性,但降低了GSH-Px的活性。相比之下,可可脂降低了胸腺和肝脏中的CAT活性,大豆油降低了胸腺中的CAT活性。3. 淋巴器官中硫代巴比妥酸反应性物质的含量未发生改变,但血浆中的含量增加了。

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