Heinrich-Ramm R, Lehnert G, Angerer J
Zentralinstitut für Arbeitsmedizin/Ordinariat für Arbeitsmedizin, Universität Hamburg, Germany.
Ann Ist Super Sanita. 1996;32(2):247-51.
According to a technical guideline for dangerous substances (TRGS 410) issued in 1979 by the Ministry of Labour of the Federal Republic of Germany, toxicological analyses in biological materials must be performed under conditions of "statistical quality control". The German Society for Occupational and Environmental Medicine is entrusted with the organization of the German external quality assessment scheme (EQAS). Since 1982 about 100 laboratories regularly take part in each run. Blood and urine samples spiked with two different concentrations (A, B) are distributed to the laboratories. Since 1991 additional samples with environmental exposure levels are also included in the EQAS. A laboratory is certified as successful if both its results (A, B) fall within the tolerance range given by the reference laboratories. The thirteenth (1994) external quality assessment exercise included blood and urine samples containing 21 inorganic and 29 organic substances, besides 8 inorganic and 14 organic analytes within the environmental concentration range.
根据德意志联邦共和国劳工部1979年发布的一项危险物质技术指南（TRGS 410），生物材料中的毒理学分析必须在“统计质量控制”条件下进行。德国职业与环境医学协会受托组织德国外部质量评估计划（EQAS）。自1982年以来，每次检测约有100个实验室定期参与。向各实验室分发添加了两种不同浓度（A、B）的血液和尿液样本。自1991年起，EQAS中还纳入了具有环境暴露水平的额外样本。如果一个实验室的结果（A、B）都落在参考实验室给出的公差范围内，则该实验室被认证为成功。第13次（1994年）外部质量评估活动包括含有21种无机物质和29种有机物质的血液和尿液样本，此外还有环境浓度范围内的8种无机分析物和14种有机分析物。
