慢性肝病中的肉碱代谢
Carnitine metabolism in chronic liver disease.
作者信息
Krähenbühl S
机构信息
Department of Internal Medicine, University Hospital, Zurich, Switzerland.
出版信息
Life Sci. 1996;59(19):1579-99. doi: 10.1016/0024-3205(96)00343-8.
PMID:8913324
Abstract
The liver is a central organ for carnitine metabolism and for the distribution of carnitine to the body. It is therefore not surprising that carnitine metabolism is impaired in patients and experimental animals with certain types of chronic liver disease. In this review, the changes in carnitine metabolism associated with chronic liver disease and the role of carnitine as a therapeutic agent in some of these conditions are discussed.
摘要
肝脏是肉碱代谢以及将肉碱分布至全身的核心器官。因此，在患有某些类型慢性肝病的患者和实验动物中肉碱代谢受损也就不足为奇了。在这篇综述中，我们将讨论与慢性肝病相关的肉碱代谢变化以及肉碱在其中某些情况下作为治疗药物的作用。
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