Kaipiainen-Seppänen O, Aho K, Isomäki H, Laakso M
Department of Medicine, Kuopio University Hospital, Finland.
Clin Exp Rheumatol. 1996 Sep-Oct;14(5):537-42.
To obtain information on changes in the age distribution of new cases of rheumatoid arthritis (RA) in Finland.
The present study covered those subjects entitled under the nationwide sickness insurance scheme to receive specially reimbursed medication for RA in 5/21 central hospital districts in Finland (population base about one million adults) in 1975, 1980, 1985, and 1990.
During the four study years 1321 incident cases occurred, which satisfied the American Rheumatism Association 1987 classification criteria for RA. The mean age at diagnosis increased by 7.6 years from 1975 (50.2 years) to 1990 (57.8 years). No appreciable differences occurred between men and women. The incidence rates declined in the younger age groups.
The epidemiology of RA is in a dynamic state. The trends may reflect marked changes in the host-environment relationship.
获取有关芬兰类风湿关节炎(RA)新发病例年龄分布变化的信息。
本研究涵盖了1975年、1980年、1985年和1990年芬兰5/21个中央医院区(约有100万成年人的人口基数)中符合全国疾病保险计划资格、可获得RA特殊报销药物的人群。
在这四个研究年份中,共出现了1321例符合美国风湿病协会1987年RA分类标准的新发病例。诊断时的平均年龄从1975年的50.2岁增加到1990年的57.8岁,增加了7.6岁。男性和女性之间没有明显差异。较年轻年龄组的发病率有所下降。
RA的流行病学处于动态变化中。这些趋势可能反映了宿主与环境关系的显著变化。