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经皮神经根/硬膜外皮质类固醇注射治疗神经根型颈椎病的疗效:一项具有独立临床评估的前瞻性研究

Outcome of cervical radiculopathy treated with periradicular/epidural corticosteroid injections: a prospective study with independent clinical review.

作者信息

Bush K, Hillier S

机构信息

Physiotherapy Practice, London, UK.

出版信息

Eur Spine J. 1996;5(5):319-25. doi: 10.1007/BF00304347.

DOI:10.1007/BF00304347
PMID:8915637
Abstract

This prospective study with independent clinical review was set up to monitor the clinical outcome of patients when using serial periradicular/epidural corticosteroid injection techniques in managing cervical radiculopathy. Over a 10 year period, between 1986 and 1995, a consecutive series of 68 secondary referral patients presenting with cervical radiculopathy were entered into the study. There were 57 men (84%) and 11 women (16%) of average age 47 years (range 31-65 years). The average duration of symptoms prior to presentation was 2 months (range 1-12 months). All patients apart from one had neurological signs. Of the 64 patients (94%) who underwent imaging, relevant pathology thought to correlate with the clinical presentation was demonstrated in all but one patient. Serial periradicular/ epidural corticosteroid injections were used to control pain; an average of 2.5 injections was administered per patient (range 1-6). Patients underwent a final clinical examination when their pain had remained satisfactorily under control for an average of 7 months (range 1-23 months). They subsequently were reassessed, by an independent clinician, at an average of 39 months (range 4-112 months) after initial presentation, via a telephone interview. Despite the fact that all 68 patients were potential surgical candidates, they all made a satisfactory recovery without the need for surgical intervention. Forty-eight patients (76%) did not experience any arm pain, and of the 15 patients (24%) who did, this improved from 10 to an average of 2 (range 1-4) on a 10-point pain scale. Thus, patients with cervical radiculopathy make a satisfactory recovery with serial periradicular/epidural corticosteroid injections without the need for surgical intervention.

摘要

这项具有独立临床评估的前瞻性研究旨在监测采用系列性神经根周围/硬膜外皮质类固醇注射技术治疗颈神经根病时患者的临床结局。在1986年至1995年的10年期间,连续纳入了68例因颈神经根病而进行二次转诊的患者。其中男性57例(84%),女性11例(16%),平均年龄47岁(范围31 - 65岁)。就诊前症状的平均持续时间为2个月(范围1 - 12个月)。除1例患者外,所有患者均有神经体征。在接受影像学检查的64例患者(94%)中,除1例患者外,其余所有患者均显示出与临床表现相关的病理改变。采用系列性神经根周围/硬膜外皮质类固醇注射来控制疼痛;每位患者平均注射2.5次(范围1 - 6次)。当患者的疼痛在平均7个月(范围1 - 23个月)内得到满意控制时,接受了最终临床检查。随后,由一名独立的临床医生通过电话访谈,在初次就诊后平均39个月(范围4 - 112个月)对患者进行重新评估。尽管所有68例患者均为潜在的手术候选者,但他们均获得了满意的恢复,无需进行手术干预。48例患者(76%)未再出现手臂疼痛,在仍有手臂疼痛的15例患者(24%)中,其疼痛程度从10分制的10分改善至平均2分(范围1 - 4分)。因此,颈神经根病患者通过系列性神经根周围/硬膜外皮质类固醇注射可获得满意的恢复,无需进行手术干预。

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Spine (Phila Pa 1976). 1993 May;18(6):730-6. doi: 10.1097/00007632-199305000-00010.
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Posterior cervical laminoforaminotomy for radiculopathy: review of 172 cases.后路颈椎板间孔切开术治疗神经根病:172例病例回顾
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Robinson anterior cervical discectomy and arthrodesis for cervical radiculopathy. Long-term follow-up of one hundred and twenty-two patients.
评估退行性颈椎神经根病运动功能障碍保守治疗与手术治疗的证据
Global Spine J. 2023 Mar;13(2):547-562. doi: 10.1177/21925682221109562. Epub 2022 Jun 16.
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Diagnosis and Treatment of Cervical Spondylotic Radiculopathy Using Selective Nerve Root Block (SNRB): Where are We Now?使用选择性神经根阻滞(SNRB)诊断和治疗神经根型颈椎病:我们目前的进展如何?
Pain Ther. 2022 Jun;11(2):341-357. doi: 10.1007/s40122-022-00357-1. Epub 2022 Feb 15.
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Do Epidural Steroid Injections Affect Outcomes and Costs in Cervical Degenerative Disease? A Retrospective MarketScan Database Analysis.硬膜外类固醇注射对颈椎退行性疾病的治疗效果和成本有何影响?一项回顾性MarketScan数据库分析。
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Cervical radiculopathy.神经根型颈椎病
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