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大鼠脑突触中的14-3-2蛋白。

14-3-2 protein in rat brain synapses.

作者信息

Rönnbäck L, Persson L, Hansson H A, Haglid K G, Grasso A

出版信息

Experientia. 1977 Aug 15;33(8):1094-5. doi: 10.1007/BF01945991.

DOI:10.1007/BF01945991
PMID:891824
Abstract

The distribution of the 14-3-2 protein in rat brain synapses was studied by immuno electron microscopy. The protein was localized to the postsynaptic web and to the postsynaptic membrane, but was also prominent both in the presynaptic membrane and in the presynaptic densities. No significant activity was observed in the synaptic vesicles.

摘要

通过免疫电子显微镜研究了14-3-2蛋白在大鼠脑突触中的分布。该蛋白定位于突触后网和突触后膜,但在突触前膜和突触前致密物中也很突出。在突触小泡中未观察到明显活性。

相似文献

1
14-3-2 protein in rat brain synapses.大鼠脑突触中的14-3-2蛋白。
Experientia. 1977 Aug 15;33(8):1094-5. doi: 10.1007/BF01945991.
2
Resolution of proteins from subfractions of nerve endings.从神经末梢亚组分中分离蛋白质。
Brain Res. 1972 Sep 15;44(1):177-87. doi: 10.1016/0006-8993(72)90373-3.
3
Phosphoproteins in postsynaptic densities.突触后致密物中的磷蛋白。
Prog Brain Res. 1982;56:49-76. doi: 10.1016/S0079-6123(08)63768-1.
4
14-3-2 protein in rat brain.大鼠脑中的14-3-2蛋白。
J Neurol Sci. 1978 Feb;35(2-3):381-90. doi: 10.1016/0022-510x(78)90018-7.
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Morphological and molecular organization of the brain postsynaptic densities.大脑突触后致密物的形态学和分子组织
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6
Immunohistochemical localisation of S-100 protein in brain.脑内S-100蛋白的免疫组织化学定位
Nature. 1975 Dec 25;258(5537):746-8. doi: 10.1038/258746a0.
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Carbohydrate composition of central nervous system synapses. Analysis of isolated synaptic junctional complexes and postsynaptic densities.中枢神经系统突触的碳水化合物组成。对分离的突触连接复合体和突触后致密物的分析。
Biochim Biophys Acta. 1976 Sep 21;448(1):57-72. doi: 10.1016/0005-2736(76)90076-6.
8
[Specific proteins of synaptic structures].[突触结构的特定蛋白质]
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Proteins of the postsynaptic density.突触后致密区的蛋白质
J Cell Biol. 1974 Nov;63(2 Pt 1):456-65. doi: 10.1083/jcb.63.2.456.
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Isolation, morphology, and protein and glycoprotein composition of synaptic junctional fractions from the brain of lower vertebrates: antigen PSD-95 as a junctional marker.低等脊椎动物大脑突触连接部分的分离、形态学以及蛋白质和糖蛋白组成:抗原PSD-95作为连接标记物
J Neurosci. 1982 Jun;2(6):722-34. doi: 10.1523/JNEUROSCI.02-06-00722.1982.

引用本文的文献

1
Changes in the levels of neural cell specific proteins in the developing rat brain.发育中大鼠大脑神经细胞特异性蛋白水平的变化
Neurochem Res. 1985 Aug;10(8):1155-72. doi: 10.1007/BF00965889.

本文引用的文献

1
The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: ultrastructural cytochemistry by a new technique.注入的辣根过氧化物酶在小鼠肾近端小管吸收的早期阶段:一种新技术的超微结构细胞化学研究
J Histochem Cytochem. 1966 Apr;14(4):291-302. doi: 10.1177/14.4.291.
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Changes in the concentrations of the two brain specific proteins, s-100 and 14-3-2, during the development of the avian optic tectum.
Brain Res. 1970 Nov 11;24(1):1-10. doi: 10.1016/0006-8993(70)90270-2.
3
The cellular localization of the two brain specific proteins, S-100 and 14-3-2.两种脑特异性蛋白S-100和14-3-2的细胞定位
Brain Res. 1970 Feb 17;18(1):25-34. doi: 10.1016/0006-8993(70)90454-3.
4
Regional changes in CNS levels of the S-100 and 14-3-2 proteins during development and aging of the mouse.小鼠发育和衰老过程中中枢神经系统中S-100和14-3-2蛋白水平的区域变化。
J Neurochem. 1972 Sep;19(9):2119-25. doi: 10.1111/j.1471-4159.1972.tb05121.x.
5
Molecular weight estimation of polypeptide chains by electrophoresis in SDS-polyacrylamide gels.通过SDS-聚丙烯酰胺凝胶电泳对多肽链进行分子量估计
Biochem Biophys Res Commun. 1967 Sep 7;28(5):815-20. doi: 10.1016/0006-291x(67)90391-9.
6
14-3-2 Protein in rat brain synaptosomes: an immunochemical study.
FEBS Lett. 1974 Mar 15;40(1):154-6. doi: 10.1016/0014-5793(74)80916-6.
7
An immunofluorescence procedure for the detection of intracellular immunoglobulins.一种用于检测细胞内免疫球蛋白的免疫荧光程序。
Clin Exp Immunol. 1969 Apr;4(4):457-72.
8
Cellular and subcellular distribution of the S-100 protein in rabbit and rat central nervous system.S-100蛋白在兔和大鼠中枢神经系统中的细胞及亚细胞分布
J Neurosci Res. 1976;2(3):175-91. doi: 10.1002/jnr.490020302.
9
Preparation and properties of the brain specific protein 14-3-2.脑特异性蛋白14-3-2的制备与性质
Brain Res. 1977 Apr 1;124(3):497-507. doi: 10.1016/0006-8993(77)90949-0.
10
Localization of 14-3-2 protein in the rat brain by immunoelectron microscopy.通过免疫电子显微镜对大鼠脑中14-3-2蛋白进行定位。
Brain Res. 1977 Feb 25;122(3):582-5. doi: 10.1016/0006-8993(77)90472-3.