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对主诉不孕的表面正常夫妇进行长期随访。

Long-term follow-up of the apparently normal couple with a complaint of infertility.

作者信息

Lenton E A, Weston G A, Cooke I D

出版信息

Fertil Steril. 1977 Sep;28(9):913-9. doi: 10.1016/s0015-0282(16)42790-1.

DOI:10.1016/s0015-0282(16)42790-1
PMID:892041
Abstract

Ninety-one couples with no obvious cause for their infertility were followed after periods of 1 to 17 years (96% were followed until they conceived or for more than 5 years). All of the couples had been fully investigated and no specific abnormality had been demonstrated. The majority of women (88%) had primary infertility of at least 2 years' duration, although a small number (12%) had had one or more first-trimester abortions and were thus classified as having secondary infertility. Cumulative conception rates (using life tables) at the end of 7 years were 36.2% for the primary infertility group and 78.8% for the women with secondary infertility. Of those couples achieving a first pregnancy and desiring a second, only 44.3% had conceived at the end of another 4-year period. These rates are markedly lower than the published conception rates of a normal population.

摘要

91对不明原因不孕的夫妇接受了为期1至17年的随访(96%的夫妇随访至受孕或超过5年)。所有夫妇均接受了全面检查,未发现特定异常。大多数女性(88%)患有至少2年的原发性不孕,尽管少数(12%)有过一次或多次孕早期流产,因此被归类为继发性不孕。原发性不孕组在7年末的累积受孕率(使用生命表)为36.2%,继发性不孕女性为78.8%。在那些首次怀孕并渴望再次怀孕的夫妇中,在接下来的4年结束时,只有44.3%受孕。这些比率明显低于正常人群公布的受孕率。

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