意大利四个地区尿中乙撑硫脲的参考值（多中心研究）。

Reference values of urinary ethylenethiourea in four regions of Italy (multicentric study).

作者信息

Aprea C, Betta A, Catenacci G, Lotti A, Minoia C, Passini W, Pavan I, Saverio Robustelli della Cuna F, Roggi C, Ruggeri R, Soave C, Sciarra G, Vannini P, Vitalone V

机构信息

Institute of Occupational Medicine, University of Siena, Italy.

出版信息

Sci Total Environ. 1996 Nov 29;192(1):83-93. doi: 10.1016/0048-9697(96)05300-4.

DOI:10.1016/0048-9697(96)05300-4

PMID:8921624

Abstract

The results of a study in which urinary ethylenethiourea (ETU) was assayed in the general population (167 subjects) of four Regions of Italy (Veneto, Lombardy, Piedmont and Trentino Alto Adige) are reported. The results are compared with those in a population of 97 subjects from Rovescala, a hillside wine-producing town a few kilometers from Pavia, where ethylenebisdithiocarbamates are sprayed by helicopter. It was found that an average of 24% of the populations of the four regions, taken together, had urinary ETU levels above detection limits (1.0 microgram 1(-1)) as compared to 37% of the population of Rovescala. The ranges of concentration were 0.8-8.3 micrograms 1(-1) for the four regions and 0.9-61.4 micrograms 1(-1) for Rovescala. Statistically significant variables for urinary ETU levels were smoking and wine drinking.

摘要

本文报告了一项针对意大利四个地区（威尼托、伦巴第、皮埃蒙特和特伦蒂诺-上阿迪杰）普通人群（167名受试者）尿液中乙撑硫脲（ETU）的检测研究结果。研究结果与来自罗韦斯卡拉萨的97名受试者的结果进行了比较，罗韦斯卡拉萨是一个距离帕维亚几公里的山坡葡萄酒生产小镇，在那里人们用直升机喷洒乙撑双二硫代氨基甲酸盐。研究发现，四个地区的总人口中平均有24%的人尿液中ETU水平高于检测限（1.0微克/升），而罗韦斯卡拉萨的这一比例为37%。四个地区的浓度范围为0.8 - 8.3微克/升，罗韦斯卡拉萨为0.9 - 61.4微克/升。尿液中ETU水平的统计学显著变量是吸烟和饮酒。