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日本胃癌大规模筛查中检测出的胃癌的结局

Outcome of gastric carcinoma detected by gastric mass survey in Japan.

作者信息

Kaneko E, Nakamura T, Umeda N, Fujino M, Niwa H

出版信息

Gut. 1977 Aug;18(8):626-30. doi: 10.1136/gut.18.8.626.

Abstract

The outcome was studied of gastric carcinoma found in six selected mass survey groups. One-hundred-and-thirty-seven cases of gastric carcinoma were detected and followed-up postoperatively for 16 years at the longest. They consisted of 55 cases of early and 74 of advanced carcinoma with eight cases of unknown depth of involvement. Early carcinoma amounted to 42-6% of the cases with known depth of involvement. The relative five-year and 10-year survival rates calculated by the method of Ederer et al. (1961) in the 137 cases were 0-628 and 0-642, respectively, and those for early carcinoma were 0-959 and 1-016. These survival rates are remarkably high. The five-year survival rate in those who were followed-up after operation for more than five years (83 cases) was 0-554, which is much higher than that of the outpatient cases, who presented themselves for medical advice with some symptoms. The good prognosis is largely explained by a high incidence of early gastric carcinoma in the cases detected in the mass survey. Where methods of screening were concerned, the use of the gastrocamera markedly improved the detection rate of gastric carcinoma.

摘要

对六个选定的大规模调查群体中发现的胃癌患者的预后情况进行了研究。共检测出137例胃癌患者,并对其进行术后随访,最长随访16年。其中早期胃癌55例,进展期胃癌74例,8例浸润深度不明。在已知浸润深度的病例中,早期胃癌占42.6%。采用埃德勒等人(1961年)的方法计算,这137例患者的相对五年和十年生存率分别为0.628和0.642,早期胃癌患者的相对五年和十年生存率分别为0.959和1.016。这些生存率非常高。术后随访超过五年的患者(83例)的五年生存率为0.554,远高于因出现某些症状前来就医的门诊患者。大规模调查中检测出的病例早期胃癌发病率高,在很大程度上解释了预后良好的原因。就筛查方法而言,使用胃镜显著提高了胃癌的检出率。

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