Barazanji K W, Ramanathan M, Johnson R L, Hsia C C
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235-9034, USA.
J Appl Physiol (1985). 1996 Apr;80(4):1258-62. doi: 10.1152/jappl.1996.80.4.1258.
To lower the cost and improve accessibility of the rebreathing technique for measuring cardiopulmonary function during exercise, we implemented a fast-response infrared (IR) gas-analyzer system to simultaneously measure lung diffusing capacity, cardiac output lung tissue volume, and lung volume by a rebreathing technique in five healthy subjects at rest and during steady-state exercise. Interferences by water vapor and CO2 on the analyzer were determined and corrected for. During rebreathing, a gas mixture of 0.4% C2H2-0.3% CH4-9% He-30% O2, and either 0.3% C18O or 0.3% C16O in a balance of N2 was simultaneously sampled by both a mass spectrometer and the IR analyzer, permitting paired comparisons. Measurements obtained by the two devices were not significantly different. We conclude that this modified rebreathing technique using the IR analyzer is accurate for the measurement of cardiopulmonary function at rest and during exercise.
为了降低运动期间采用重复呼吸技术测量心肺功能的成本并提高其可及性，我们实施了一种快速响应红外（IR）气体分析仪系统，通过重复呼吸技术在5名健康受试者静息和稳态运动期间同时测量肺扩散容量、心输出量、肺组织容量和肺容积。确定并校正了分析仪中水蒸气和二氧化碳的干扰。在重复呼吸期间，由质谱仪和红外分析仪同时采集0.4% C2H2 - 0.3% CH4 - 9% He - 30% O2以及在N2平衡中含有0.3% C18O或0.3% C16O的混合气体样本，以便进行配对比较。两种设备获得的测量结果无显著差异。我们得出结论，这种使用红外分析仪的改良重复呼吸技术对于静息和运动期间心肺功能的测量是准确的。
