Hosoya N, Mimura T, Enokawa Y, Mizuno T, Hamasaki K, Matsuyama T, Matsuhashi N, Yotsumoto H, Yazaki Y
Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo.
Intern Med. 1995 Dec;34(12):1164-7. doi: 10.2169/internalmedicine.34.1164.
A 56-year-old woman with overlap syndrome of progressive systemic sclerosis (PSS), Sjogren's syndrome, and polymyositis is reported. She developed complete atrioventricular (AV) block and progressive bilateral hilar adenopathy, and was diagnosed as having sarcoidosis by histological examination of the hilar lymph nodes biopsied thoracoscopically. Although coexistence of one or two autoimmune diseases with sarcoidosis is not uncommon, coexistence of three or more autoimmune diseases with sarcoidosis is rare. To our knowledge, the described case is the first case in which the three above-mentioned autoimmune diseases were accompanied by myocardial sarcoidosis.
报道了一名56岁患有进行性系统性硬化症（PSS）、干燥综合征和多发性肌炎重叠综合征的女性。她出现了完全性房室传导阻滞和进行性双侧肺门淋巴结肿大，并通过胸腔镜活检的肺门淋巴结组织学检查被诊断为结节病。虽然结节病与一两种自身免疫性疾病并存并不罕见，但结节病与三种或更多自身免疫性疾病并存则很罕见。据我们所知，所描述的病例是上述三种自身免疫性疾病伴有心肌结节病的首例。
