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乙酰胆碱酯酶活性作为大鼠杏仁体基底外侧复合体成熟的标志物

Acetylcholinesterase activity as a marker of maturation of the basolateral complex of the amygdaloid body in the rat.

作者信息

Berdel B, Moryś J, Maciejewska B, Narkiewicz O

机构信息

Department of Anatomy, Medical University of Gdańsk, Poland.

出版信息

Int J Dev Neurosci. 1996 Aug;14(5):543-9.

PMID:8930685
Abstract

Development and maturation of the basolateral complex of the amygdaloid body were studied in fetal and postnatal rat brains. In cresyl violet-stained sections the basolateral complex was distinguishable at the 17th prenatal day. On about the 14th postnatal day, it showed all the features of the adult structure. The acetylcholinesterase activity appeared in neuropil of the basolateral complex on the seventh postnatal day; it increased slowly up to the 60th day. After that age, the acetylcholinesterase activity was stable in all parts of the basolateral complex and corresponded to its cytoarchitectonic differentiation. Our results suggest that the process of maturation of the amygdaloid basolateral complex, being related to the ingrowing of the cholinergic fibers from the basal forebrain, lasts at least up to the end of the second month of postnatal life.

摘要

对胎鼠和新生大鼠脑杏仁核基底外侧复合体的发育和成熟过程进行了研究。在甲酚紫染色切片中,基底外侧复合体在产前第17天即可辨别。大约在出生后第14天,它呈现出成年结构的所有特征。乙酰胆碱酯酶活性在出生后第7天出现在基底外侧复合体的神经毡中;到第60天时缓慢增加。在该年龄之后,乙酰胆碱酯酶活性在基底外侧复合体的所有部位都保持稳定,并与其细胞构筑分化相对应。我们的结果表明,杏仁核基底外侧复合体的成熟过程与来自基底前脑的胆碱能纤维长入有关,至少持续到出生后第二个月末。

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