• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling.真核生物对高丝氨酸内酯介导的原核生物信号传导的干扰。
J Bacteriol. 1996 Nov;178(22):6618-22. doi: 10.1128/jb.178.22.6618-6622.1996.
2
Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein.来自美丽笛海绵的卤代呋喃酮通过从其受体蛋白上取代酰化高丝氨酸内酯(AHL)信号来抑制AHL介导的基因表达的证据。
Microbiology (Reading). 1999 Feb;145 ( Pt 2):283-291. doi: 10.1099/13500872-145-2-283.
3
Quorum sensing in Serratia.沙雷氏菌中的群体感应
FEMS Microbiol Rev. 2007 Jul;31(4):407-24. doi: 10.1111/j.1574-6976.2007.00071.x. Epub 2007 Apr 25.
4
How Delisea pulchra furanones affect quorum sensing and swarming motility in Serratia liquefaciens MG1.美丽德尔isea呋喃酮如何影响液化沙雷氏菌MG1中的群体感应和群体游动性。
Microbiology (Reading). 2000 Dec;146 Pt 12:3237-3244. doi: 10.1099/00221287-146-12-3237.
5
N-acylhomoserine lactone-dependent cell-to-cell communication and social behavior in the genus Serratia.粘质沙雷氏菌属中N-酰基高丝氨酸内酯依赖性细胞间通讯及群体行为
Int J Med Microbiol. 2006 Apr;296(2-3):117-24. doi: 10.1016/j.ijmm.2006.01.033. Epub 2006 Feb 17.
6
Intracellular Ca(2+) mobilization and kinase activity during acylated homoserine lactone-dependent quorum sensing in Serratia liquefaciens.粘质沙雷氏菌中酰化高丝氨酸内酯依赖性群体感应过程中的细胞内钙离子动员和激酶活性
J Biol Chem. 2001 Mar 2;276(9):6468-72. doi: 10.1074/jbc.M009223200. Epub 2000 Dec 1.
7
Quorum sensing signal molecules (acylated homoserine lactones) in gram-negative fish pathogenic bacteria.革兰氏阴性鱼类病原菌中的群体感应信号分子(酰化高丝氨酸内酯)
Dis Aquat Organ. 2005 Jun 14;65(1):43-52. doi: 10.3354/dao065043.
8
Reaction of acylated homoserine lactone bacterial signaling molecules with oxidized halogen antimicrobials.酰化高丝氨酸内酯细菌信号分子与氧化型卤素抗菌剂的反应。
Appl Environ Microbiol. 2001 Jul;67(7):3174-9. doi: 10.1128/AEM.67.7.3174-3179.2001.
9
Visualization of N-acylhomoserine lactone-mediated cell-cell communication between bacteria colonizing the tomato rhizosphere.番茄根际定殖细菌间N-酰基高丝氨酸内酯介导的细胞间通讯可视化
Appl Environ Microbiol. 2001 Dec;67(12):5761-70. doi: 10.1128/AEM.67.12.5761-5770.2001.
10
Beyond quorum sensing: the complexities of prokaryotic parliamentary procedures.超越群体感应:原核生物议会程序的复杂性
Anal Bioanal Chem. 2007 Jan;387(2):391-8. doi: 10.1007/s00216-006-0730-9. Epub 2006 Sep 5.

引用本文的文献

1
The Global Challenge of Antimicrobial Resistance: Mechanisms, Case Studies, and Mitigation Approaches.抗菌药物耐药性的全球挑战:机制、案例研究及缓解方法
Health Sci Rep. 2025 Jul 23;8(7):e71077. doi: 10.1002/hsr2.71077. eCollection 2025 Jul.
2
In silico and in vitro analysis of diethyl phthalate as a quorum sensing inhibitor and its antitumor evaluation against MDA-MB-231 cell lines.邻苯二甲酸二乙酯作为群体感应抑制剂的计算机模拟和体外分析及其对MDA-MB-231细胞系的抗肿瘤评估。
Mol Divers. 2025 Apr 28. doi: 10.1007/s11030-025-11202-w.
3
Oxirapentyn A, Derived from Marine Amphichorda felina, Effectively Inhibits Quorum Sensing and Biofilm Formation Against Chromobacterium violaceum.源自海洋猫鲨的奥西拉喷汀A可有效抑制紫色杆菌的群体感应和生物膜形成。
Curr Microbiol. 2025 Mar 27;82(5):215. doi: 10.1007/s00284-025-04202-4.
4
A review of quorum-sensing and its role in mediating interkingdom interactions in the ocean.群体感应及其在介导海洋中跨界相互作用的作用综述。
Commun Biol. 2025 Feb 5;8(1):179. doi: 10.1038/s42003-025-07608-9.
5
Role of bacterial quorum sensing in plant growth promotion.细菌群体感应在促进植物生长中的作用。
World J Microbiol Biotechnol. 2024 Dec 26;41(1):18. doi: 10.1007/s11274-024-04232-3.
6
Beyond Antibiotics: What the Future Holds.超越抗生素:未来会怎样。
Antibiotics (Basel). 2024 Sep 25;13(10):919. doi: 10.3390/antibiotics13100919.
7
Advancing Antibiotic-Resistant Microbe Combat: Nanocarrier-Based Systems in Combination Therapy Targeting Quorum Sensing.推进抗抗生素耐药微生物斗争:基于纳米载体的系统在靶向群体感应联合治疗中的应用
Pharmaceutics. 2024 Sep 3;16(9):1160. doi: 10.3390/pharmaceutics16091160.
8
Quorum Sensing Inhibitors: An Alternative Strategy to Win the Battle against Multidrug-Resistant (MDR) Bacteria.群体感应抑制剂:对抗多药耐药(MDR)细菌的另一种策略。
Molecules. 2024 Jul 24;29(15):3466. doi: 10.3390/molecules29153466.
9
Characterization of natural product inhibitors of quorum sensing reveals competitive inhibition of RhlR by -vanillin.天然产物群体感应抑制剂的特性研究揭示了β-香草醛对 RhlR 的竞争性抑制作用。
Microbiol Spectr. 2024 Sep 3;12(9):e0068124. doi: 10.1128/spectrum.00681-24. Epub 2024 Jul 24.
10
Characterization of natural product inhibitors of quorum sensing in reveals competitive inhibition of RhlR by -vanillin.群体感应天然产物抑制剂的表征表明,香草醛对RhlR具有竞争性抑制作用。
bioRxiv. 2024 Mar 13:2024.02.24.581676. doi: 10.1101/2024.02.24.581676.

本文引用的文献

1
Impact of CLOD Pathogen on Pacific Coral Reefs.克洛德病原体对太平洋珊瑚礁的影响。
Science. 1995 Mar 3;267(5202):1356-60. doi: 10.1126/science.267.5202.1356.
2
Involvement of N-acyl-L-hormoserine lactone autoinducers in controlling the multicellular behaviour of Serratia liquefaciens.N-酰基-L-高丝氨酸内酯自诱导物参与控制液化沙雷氏菌的多细胞行为。
Mol Microbiol. 1996 Apr;20(1):127-36. doi: 10.1111/j.1365-2958.1996.tb02495.x.
3
Differentiation of Serratia liquefaciens into swarm cells is controlled by the expression of the flhD master operon.液化沙雷氏菌向群体游动细胞的分化受flhD主操纵子表达的控制。
J Bacteriol. 1996 Jan;178(2):554-9. doi: 10.1128/jb.178.2.554-559.1996.
4
Cell differentiation of Proteus mirabilis is initiated by glutamine, a specific chemoattractant for swarming cells.奇异变形杆菌的细胞分化由谷氨酰胺引发,谷氨酰胺是一种对群游细胞有特异性的趋化剂。
Mol Microbiol. 1993 Apr;8(1):53-60. doi: 10.1111/j.1365-2958.1993.tb01202.x.
5
Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators.细菌中的群体感应:细胞密度响应转录调节因子的LuxR-LuxI家族
J Bacteriol. 1994 Jan;176(2):269-75. doi: 10.1128/jb.176.2.269-275.1994.
6
Dimorphic transition in Escherichia coli and Salmonella typhimurium: surface-induced differentiation into hyperflagellate swarmer cells.大肠杆菌和鼠伤寒沙门氏菌中的双态转变:表面诱导分化为多鞭毛游动细胞。
Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8631-5. doi: 10.1073/pnas.91.18.8631.
7
The bacterial 'enigma': cracking the code of cell-cell communication.细菌“谜团”:破解细胞间通讯密码
Mol Microbiol. 1995 May;16(4):615-24. doi: 10.1111/j.1365-2958.1995.tb02424.x.
8
Adsorption kinetics of laterally and polarly flagellated Vibrio.侧生和极生鞭毛弧菌的吸附动力学
J Bacteriol. 1982 Sep;151(3):1568-80. doi: 10.1128/jb.151.3.1568-1580.1982.
9
Analogs of the autoinducer of bioluminescence in Vibrio fischeri.
Arch Microbiol. 1986 Oct;146(1):35-40. doi: 10.1007/BF00690155.
10
Differentiation of Serratia marcescens 274 into swimmer and swarmer cells.粘质沙雷氏菌274分化为游动细胞和群游细胞。
J Bacteriol. 1990 Aug;172(8):4322-8. doi: 10.1128/jb.172.8.4322-4328.1990.

真核生物对高丝氨酸内酯介导的原核生物信号传导的干扰。

Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling.

作者信息

Givskov M, de Nys R, Manefield M, Gram L, Maximilien R, Eberl L, Molin S, Steinberg P D, Kjelleberg S

机构信息

Department of Microbiology, The Technical University of Denmark, Lyngby.

出版信息

J Bacteriol. 1996 Nov;178(22):6618-22. doi: 10.1128/jb.178.22.6618-6622.1996.

DOI:10.1128/jb.178.22.6618-6622.1996
PMID:8932319
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC178549/
Abstract

Acylated homoserine lactones (AHLs) play a widespread role in intercellular communication among bacteria. The Australian macroalga Delisea pulchra produces secondary metabolites which have structural similarities to AHL molecules. We report here that these metabolites inhibited AHL-controlled processes in prokaryotes. Our results suggest that the interaction between higher organisms and their surface-associated bacteria may be mediated by interference with bacterial regulatory systems.

摘要

酰化高丝氨酸内酯(AHLs)在细菌间的细胞间通讯中发挥着广泛作用。澳大利亚大型海藻美丽德尔藻产生的次生代谢产物与AHL分子在结构上有相似之处。我们在此报告,这些代谢产物抑制了原核生物中AHL控制的过程。我们的结果表明,高等生物与其表面相关细菌之间的相互作用可能是通过干扰细菌调节系统来介导的。