肝硬化患者大脑中的T1和T2改变。
T1 and T2 alterations in the brains of patients with hepatic cirrhosis.
作者信息
Vymazal J, Babis M, Brooks R A, Filip K, Dezortova M, Hrncarkova H, Hajek M
机构信息
Neuroimaging Branch, NINDS, National Institutes of Health, Bethesda, MD, USA.
出版信息
AJNR Am J Neuroradiol. 1996 Feb;17(2):333-6.
PURPOSE
To determine whether previously reported T1-weighted MR hyperintensities in the brains of patients with hepatic cirrhosis are accompanied by changes in T2.
METHODS
We measured T1 and T2 in the brains of 10 patients with chronic liver disease and 7 age-matched healthy volunteers, using classic spin-echo sequences with multiple saturation recovery times and multiple echoes.
RESULTS
Both T1 and T2 were shortened in the basal ganglia, cortex, and white matter of the patients, with the greatest shortening in the globus pallidus, where 1/T1 was increased by 0.76 s-1 or 74% and 1/T2 by 1.45 s-1 or 11%.
CONCLUSIONS
The T1 changes were accompanied by T2 changes of greater magnitude that were not as visible because T2 is normally much shorter than T1, especially in the globus pallidus.
目的
确定先前报道的肝硬化患者大脑中T1加权磁共振高信号是否伴有T2变化。
方法
我们使用具有多个饱和恢复时间和多个回波的经典自旋回波序列，测量了10例慢性肝病患者和7名年龄匹配的健康志愿者大脑中的T1和T2。
结果
患者的基底神经节、皮质和白质中T1和T2均缩短，苍白球缩短最明显，其中1/T1增加0.76 s-1或74%，1/T2增加1.45 s-1或11%。
结论
T1变化伴有幅度更大的T2变化，但由于T2通常比T1短得多，所以不太明显，尤其是在苍白球中。
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