Tomoeda C K, Bayles K A, Trosset M W, Azuma T, McGeagh A
Department of Speech and Hearing Sciences, University of Arizona, Tucson 85721-0071, USA.
Alzheimer Dis Assoc Disord. 1996 Winter;10(4):204-15. doi: 10.1097/00002093-199601040-00006.
To examine the relation of dementia severity to the quality and quantity of oral discourse of individuals with Alzheimer disease (AD), a picture description task was administered to elicit oral discourse samples from 63 AD subjects, five individuals with very mild cognitive impairment, and 52 normal controls. Eight measures of discourse were used: total words, information units, conciseness, circumlocutions, frustrations, aborted phrases, revisions, and ideational repetitions. Information units, which decreased with increased dementia severity, proved to be the best measure for evaluating the effects of AD on oral descriptive discourse. The conciseness index also decreased with increased dementia severity, and a significantly greater proportion of AD discourse samples contained ideational repetitions. Circumlocutions and frustrations rarely occurred, and although the discourse of AD subjects was more likely to contain an aborted phrase, the frequency of aborted phrases did not vary by stage of dementia. Revisions were commonly observed in the discourse of both normal controls and AD subjects and did not differentiate the two groups.
为研究痴呆严重程度与阿尔茨海默病（AD）患者口语表达的质量和数量之间的关系，我们对63名AD患者、5名轻度认知障碍患者和52名正常对照者进行了图片描述任务，以获取口语样本。我们使用了八项话语指标：总单词数、信息单元、简洁性、迂回表达、挫折感、中断短语、修正和概念重复。随着痴呆严重程度的增加，信息单元数量减少，这被证明是评估AD对口语描述性话语影响的最佳指标。简洁性指数也随着痴呆严重程度的增加而降低，并且AD话语样本中概念重复的比例显著更高。迂回表达和挫折感很少出现，尽管AD患者的话语更有可能包含中断短语，但中断短语的频率在痴呆各阶段并无差异。正常对照者和AD患者的话语中都普遍观察到修正，且这一指标无法区分两组。
