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单病例试验。慢性疲劳综合征患者的管理:两例病例报告。

N of 1 trials. Managing patients with chronic fatigue syndrome: two case reports.

作者信息

Wiebe E

机构信息

Department of Family Practice, University of British Columbia, Vancouver.

出版信息

Can Fam Physician. 1996 Nov;42:2214-7.

Abstract

Chronic fatigue syndrome is a heterogeneous condition with as proves effective treatment. I present two case reports in which N of 1 trials helped me make management decisions. High-dose vitamin B12 injections were ineffective in one case; nimodipine was very effective in the other case.

摘要

慢性疲劳综合征是一种异质性疾病,目前尚无经证实有效的治疗方法。我介绍两例病例报告,其中单病例试验帮助我做出了管理决策。高剂量维生素B12注射在一例中无效;尼莫地平在另一例中非常有效。

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本文引用的文献

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Chronic fatigue syndrome: a working case definition.慢性疲劳综合征:实用病例定义
Ann Intern Med. 1988 Mar;108(3):387-9. doi: 10.7326/0003-4819-108-3-387.

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