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西班牙巴伦西亚的空气污染与死亡率:一项采用APHEA方法的研究

Air pollution and mortality in Valencia, Spain: a study using the APHEA methodology.

作者信息

Ballester F, Corella D, Pérez-Hoyos S, Hervás A

机构信息

Department of Epidemiology and Statistics, Institut Valencià d'Estudis en Salut Pública (IVESP), Valencia, Spain.

出版信息

J Epidemiol Community Health. 1996 Oct;50(5):527-33. doi: 10.1136/jech.50.5.527.

Abstract

STUDY OBJECTIVE

To assess the short term relationship between daily air pollution indicators (black smoke and sulphur dioxide (SO2)) and mortality in Valencia.

DESIGN

This was an ecological study using time series data with application of Poisson regression. Daily variations in four selected outcome variables (total mortality, mortality in those over 70 years of age, and cardiovascular and respiratory mortality) were considered in relation to daily variations in air pollution levels for the period 1991-93.

SETTING

The city of Valencia, Spain.

MAIN RESULTS

The mean daily mortality was 17.5, and the average daily levels of air pollutants from the three monitoring stations included in the study were, 67.7 micrograms/m3 for black smoke, and 39.9 micrograms/ m3 for SO2. A significant positive association between black smoke and three of the four outcomes in the study was found. The estimated relative risk (RR) of dying corresponding to a 10 micrograms/m3 increase in mean daily black smoke over the whole period was 1.009 (95% confidence interval (95% CI): 1.003, 1.015). For mortality in the group aged more than 70 years and for cardiovascular mortality, the RRs were 1.008 (95% CI: 1.001, 1.016) and 1.012 (95% CI: 1.003, 1.022) respectively. The association with SO2 was less clear: it was only evident during the warm season. The estimated RRs in this case were 1.007 (95% CI: 0.999, 1.015) for total mortality, 1.009 (95% CI: 1.00, 1.21) for total mortality in those older than 70, and 1.012 (95% CI: 0.995, 1.026) for cardiovascular deaths. No significant association was found between mortality from respiratory diseases and either of the two pollutants.

CONCLUSIONS

A positive relationship between air pollution and mortality was found in the short term, as has been shown in an important number of studies carried out elsewhere. Although the current levels of particulate air pollution in Valencia are not very high, they could have an effect on the number of premature deaths. Despite the fact that the association is weak, it is important at the public health level both because of the numbers of population exposed and the possibility of establishing control measures.

摘要

研究目的

评估西班牙巴伦西亚每日空气污染指标(黑烟和二氧化硫(SO₂))与死亡率之间的短期关系。

设计

这是一项生态研究,采用时间序列数据并应用泊松回归分析。研究了1991 - 1993年期间,四个选定结局变量(总死亡率、70岁以上人群死亡率、心血管疾病死亡率和呼吸系统疾病死亡率)的每日变化与空气污染水平每日变化之间的关系。

研究地点

西班牙巴伦西亚市。

主要结果

每日平均死亡率为17.5,研究中纳入的三个监测站的空气污染物平均每日水平分别为:黑烟67.7微克/立方米,SO₂ 39.9微克/立方米。研究发现,黑烟与四个结局变量中的三个存在显著正相关。在整个研究期间,黑烟平均每日浓度每增加10微克/立方米,对应的死亡估计相对风险(RR)为1.009(95%置信区间(95%CI):1.003,1.015)。对于70岁以上人群的死亡率和心血管疾病死亡率,RR分别为1.008(95%CI:1.001,1.016)和1.012(95%CI:1.003,1.022)。与SO₂的关联不太明确:仅在温暖季节明显。在此情况下,总死亡率的估计RR为1.007(95%CI:0.999,1.015),70岁以上人群总死亡率的RR为1.009(95%CI:1.00,1.21),心血管疾病死亡的RR为1.012(95%CI:0.995,1.026)。未发现呼吸系统疾病死亡率与这两种污染物中的任何一种存在显著关联。

结论

正如其他地方进行的大量研究所表明的那样,短期内发现空气污染与死亡率之间存在正相关关系。尽管巴伦西亚目前的颗粒物空气污染水平不算很高,但它们可能会对过早死亡人数产生影响。尽管这种关联较弱,但从公共卫生层面来看很重要,这既是因为暴露人群数量众多,也因为有可能制定控制措施。

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