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西班牙巴伦西亚的空气污染与心血管疾病急诊住院情况

Air pollution and emergency hospital admissions for cardiovascular diseases in Valencia, Spain.

作者信息

Ballester F, Tenías J M, Pérez-Hoyos S

机构信息

Unit of Epidemiology and Statistics, Valencian School of Studies for Health (EVES), Conselleria de Sanitat, Generalitat Valenciana, Spain.

出版信息

J Epidemiol Community Health. 2001 Jan;55(1):57-65. doi: 10.1136/jech.55.1.57.

Abstract

STUDY OBJECTIVE

To estimate the short-term association between air pollution levels and emergency hospital admissions for cardiovascular diseases in Valencia, within 1994-1996 period.

DESIGN

Daily levels of air pollution and emergency admissions for cardiovascular diseases were related to using an ecological time series design. The number of admissions was obtained from the hospital records database. Selected groups of causes were all cardiovascular diseases, heart admissions, and admissions for cerebrovascular diseases. The number of admissions for digestive diseases was used as control. Pollutants were black smoke, sulphur dioxide (SO(2)), nitrogen dioxide (NO(2)), carbon monoxide (CO) and ozone (O(3)). Magnitude of association was estimated by Poisson autoregressive regression. Estimations were calculated according the hottest (May to October) and the coldest (November to April) periods.

SETTING

City of Valencia, Spain, about 750,000 inhabitants.

PARTICIPANTS

People being admitted to the two major hospitals in the city, with a catchment area of nearly 400,000 inhabitants.

MAIN RESULTS

For the whole period, a significant association for SO(2)-24 h was found so a rise in its levels of 10 microg/m(3) was associated with an increment of 3% (95%CI 0.4 to 5.7%) in the expected number of cardiovascular admissions. A significant association for black smoke, SO(2)-24 h, SO(2)-1 h, and CO-1 h was found in the hottest semester. All these associations were verified with a lag of two days. The estimates of the associations for particles, SO(2), and CO were affected by the inclusion of the other pollutants in their models. NO(2) was independently associated with cerebrovascular admissions. There were no significant associations between air pollution and admissions for digestive diseases.

CONCLUSIONS

Current levels of air pollution and emergency cardiovascular admissions are significantly related in Valencia.

摘要

研究目的

评估1994 - 1996年期间西班牙巴伦西亚空气污染水平与心血管疾病急诊入院之间的短期关联。

设计

采用生态时间序列设计,将每日空气污染水平与心血管疾病急诊入院情况相关联。入院人数从医院记录数据库中获取。选定的病因组包括所有心血管疾病、心脏病入院病例以及脑血管疾病入院病例。消化系统疾病入院人数用作对照。污染物包括黑烟、二氧化硫(SO₂)、二氧化氮(NO₂)、一氧化碳(CO)和臭氧(O₃)。关联强度通过泊松自回归回归进行估计。估计值根据最热时期(5月至10月)和最冷时期(11月至4月)计算。

研究地点

西班牙巴伦西亚市,约有75万居民。

研究对象

该市两家主要医院收治的患者,服务人口近40万。

主要结果

在整个研究期间,发现SO₂ - 24小时存在显著关联,即其水平每升高10微克/立方米,心血管疾病预期入院人数增加3%(95%可信区间为0.4%至5.7%)。在最热的学期中,发现黑烟、SO₂ - 24小时、SO₂ - 1小时和CO - 1小时存在显著关联。所有这些关联在滞后两天时得到验证。颗粒物、SO₂和CO的关联估计值受模型中其他污染物纳入的影响。NO₂与脑血管疾病入院独立相关。空气污染与消化系统疾病入院之间无显著关联。

结论

在巴伦西亚,当前空气污染水平与心血管疾病急诊入院之间存在显著关联。

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