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[十二指肠胃食管反流的外科治疗原理]

[Rationale of the surgical treatment of duodenogastroesophageal reflux].

作者信息

Pandolfo N, Spigno L, Tronfi G, Scajola P, Mattioli F P

机构信息

Istituto di Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi di Genova.

出版信息

Ann Ital Chir. 1995 Sep-Oct;66(5):607-13.

PMID:8948797
Abstract

Patients with "intact stomach" but more frequently patients operated on the esophago-gastric junction, vagus, stomach, can develope a duodeno-gastro-esophageal reflux syndrome. We propose a rationale of the surgical treatment based upon our experiences during these last 15 years in functional studies, mainly manometric, of the entire esophago-gastro-duodeno-jejunal tract. Patients with an intect stomach: a non-demolitive ("functional") technique may be proposed each time a correctable alteration of the gastro-duodenal motility is found during the manometric study. Such interventions are the association between a fundoplicatio and Extramucose Duodenal Myotomy, Duodenal Switch, Pylorectomy. On the other side when the motor alteration is too severe and uncorrectable (Prostigmine-Test) or in presence of morphological, nearly always pre-cancerous, alterations we can perform only demolitive procedures. The intervention preferred by the AA is Total Duodenal Diversion. Patients with operated stomach: the different possible surgical procedures and their results are strictly related to the intervention preceding the onset of the reflux syndrome. In fact the better results are related to bad management and to post-operative complications during the previous intervention, rather than to an ignored pre-existing motor disorder. The Total Duodenal Diversion seems to be the must reliable also in this case, both initially and in the operated patients (conversion from Billroth II to Roux). Between 1978 and 1993 we observed 604 refluxers at 24-hour pH-recording, 209 of them with alkaline or mixed gastro-esophageal reflux. On the basis of the morphologic and functional diagnostic evaluation 64 patients underwent surgery, 36 with intact stomach and 28 with operated stomach. Good results (disappearance of esophageal symptoms and improving in gastric symptoms) were obtained in 30 (83.3%) patients with intact stomach and in 25 (89.3%) with operated stomach.

摘要

“胃完整”的患者,但在食管胃交界处、迷走神经、胃接受手术的患者更常出现十二指肠-胃-食管反流综合征。基于我们在过去15年中对整个食管-胃-十二指肠-空肠段进行功能研究(主要是测压研究)的经验,我们提出了一种手术治疗的理论依据。胃完整的患者:每次在测压研究中发现胃十二指肠动力有可纠正的改变时,可采用非破坏性(“功能性”)技术。此类干预措施包括胃底折叠术与十二指肠浆膜外肌切开术联合、十二指肠转位术、幽门切除术。另一方面,当动力改变过于严重且无法纠正(新斯的明试验)或存在形态学改变(几乎总是癌前病变)时,我们只能进行破坏性手术。作者首选的干预措施是全十二指肠转流术。胃接受手术的患者:不同的可能手术方法及其结果与反流综合征发作前的干预密切相关。事实上,较好的结果与先前干预中的管理不善和术后并发症有关,而不是与先前存在的未被重视的动力障碍有关。全十二指肠转流术在这种情况下似乎也是最可靠的,无论是最初还是在接受手术的患者中(从毕Ⅱ式转为 Roux 式)。1978年至1993年期间,我们通过24小时pH监测观察到604例反流患者,其中209例有碱性或混合性胃食管反流。根据形态学和功能诊断评估,64例患者接受了手术,36例胃完整,28例胃接受过手术。胃完整的30例患者(83.3%)和胃接受过手术的25例患者(89.3%)获得了良好的结果(食管症状消失,胃部症状改善)。

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