Nord C E
Department of Immunology, Microbiology, Pathology, and Infectious Diseases, Huddinge University Hospital, Karolinska Institute, Stockholm, Sweden.
Clin Infect Dis. 1996 Dec;23 Suppl 1:S15-8. doi: 10.1093/clinids/23.supplement_1.s15.
The in vitro activities of ciprofloxacin, ofloxacin, sparfloxacin, and DU-6859a against peptostreptococci, Clostridium perfringens, Clostridium difficile, Bacteroides fragilis, Porphyromonas, Prevotella, and Fusobacterium were determined by an agar dilution method. These activities were compared with those of piperacillin/tazobactam, cefoxitin, imipenem, clindamycin, and metronidazole. Imipenem, metronidazole, and DU-6859a were the most active antimicrobial agents that were tested. The in vitro activity of DU-6859a was superior to those of ciprofloxacin, lomefloxacin, ofloxacin, and sparfloxacin.
采用琼脂稀释法测定了环丙沙星、氧氟沙星、司帕沙星和DU - 6859a对消化链球菌、产气荚膜梭菌、艰难梭菌、脆弱拟杆菌、卟啉单胞菌、普雷沃菌和梭杆菌的体外活性。将这些活性与哌拉西林/他唑巴坦、头孢西丁、亚胺培南、克林霉素和甲硝唑的活性进行了比较。亚胺培南、甲硝唑和DU - 6859a是所测试的活性最强的抗菌药物。DU - 6859a的体外活性优于环丙沙星、洛美沙星、氧氟沙星和司帕沙星。
